Transfer of estradiol to human milk. [Radioimmunoassay]

Journal Article · Wed Nov 15 00:00:00 EST 1978 · Am. J. Obstet. Gynecol.; (United States)

OSTI ID:6802889

Nilsson, S; Nygren, K G; Johansson, E D.B.

A radioimmunoassay for the measurement of estradiol in human milk is evaluated. The detection limit was found to be 25 pg of estradiol per milliliter of milk. In milk samples collected from four lactating women during three to four months and from one pregnant and lactating woman, the concentration of estradiol was found to be below the detection limit of the assay. When six lactating women were given vaginal suppositories containing 50 or 100 mg of estradiol, it was possible to estimate the estradiol concentration in milk. A ratio of transfer of estradiol from plasma to milk during physiologic conditions is calculated to be less than 100 : 10.

• OSTI ID: 6802889
• Journal Information: Am. J. Obstet. Gynecol.; (United States), Vol. 132:6
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
59 BASIC BIOLOGICAL SCIENCES
ESTRADIOL
RADIOIMMUNOASSAY
MILK
BLOOD PLASMA
IMMUNE SERUMS
LACTATION
PREGNANCY
TRITIUM COMPOUNDS
WOMEN
ANIMALS
BIOLOGICAL MATERIALS
BLOOD
BODY FLUIDS
ESTRANES
ESTROGENS
FEMALES
FOOD
HORMONES
HYDROXY COMPOUNDS
ISOTOPE APPLICATIONS
LABELLED COMPOUNDS
MAMMALS
MAN
ORGANIC COMPOUNDS
PRIMATES
RADIOASSAY
STEROID HORMONES
STEROIDS
TRACER TECHNIQUES
VERTEBRATES
550601* - Medicine- Unsealed Radionuclides in Diagnostics
551001 - Physiological Systems- Tracer Techniques