Absence of transient elevated uv resistance during germination of Bacillus subtilis spores lacking small, acid-soluble spore proteins. cap alpha. and. beta

Journal Article · Wed Jun 01 04:00:00 EDT 1988 · J. Bacteriol.; (United States)

OSTI ID:6801166

Setlow, B; Setlow, P

Dormant spores of various Bacillus species are much more resistant to UV irradiation than are the corresponding vegetative cells. This elevated spore UV resistance appears to have two causes. First, UV irradiation of spores does not produce the pyrimidine dimers formed in vegetative-cell DNA, but rather produces several other photoproducts, the most predominant of which is termed the spore photoproduct, a 5-thyminyl-5,6-dihydrothymine adduct (1, 10). Second, spores have at least two mechanisms which efficiently repair this spore photoproduct during spore germination, including one which monomerizes the adduct back to two thymines. This study shows that germinating spores of bacillus subtilis mutants which lack small, acid-soluble spore proteins ..cap alpha.. and ..beta.. did not exhibit the transient elevated UV resistance seen during germination of wild-type spores.

• Research Organization: Univ. of Connecticut Health Center, Farmington (USA)
• OSTI ID: 6801166
• Journal Information: J. Bacteriol.; (United States), Journal Name: J. Bacteriol.; (United States) Vol. 170:6; ISSN JOBAA
• Country of Publication: United States
• Language: English

Related Subjects

560100* -- Biomedical Sciences
Applied Studies-- Radiation Effects
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BACILLUS
BACILLUS SUBTILIS
BACTERIA
BACTERIAL SPORES
ELECTROMAGNETIC RADIATION
GERMINATION
MICROORGANISMS
MUTANTS
RADIATIONS
RADIOSENSITIVITY
SPORES
ULTRAVIOLET RADIATION