Grafting of synthetic polyelectrolyte onto polymer surfaces--comparison of glow discharge and sup 60 Co-gamma-irradiation method

Journal Article · Sun Jul 01 00:00:00 EDT 1990 · Journal of Biomaterials Applications; (USA)

OSTI ID:6793197

Hari, P R; Sharma, C P ^[1]

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1. Sree Chitra Tirunal Institute for Medical Sciences Technology, Poojapura, Trivandrum (India)

Water soluble polyelectrolyte synthesized from natural rubber contains sulfamate and carboxylate groups similar to that of heparin. It is observed that synthetic heparinoid polyelectrolyte is capable of inhibiting blood coagulation. In the present study, we attempted to graft the same onto polystyrene and polymethylmethacrylate surfaces using glow discharge technique and {sup 60}Co-gamma-irradiation method, and the surfaces were compared with respect to water contact angle and platelet adhesion parameters. Heparinized surfaces are also evaluated for relative comparison.

• OSTI ID: 6793197
• Journal Information: Journal of Biomaterials Applications; (USA), Vol. 5:1; ISSN 0885-3282
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD PLATELETS
ADHESION
BLOOD COAGULATION
CATTLE
COBALT 60
HEPARIN
IN VITRO
MATERIALS TESTING
METHYL METHACRYLATE
POLYSTYRENE
SURFACE PROPERTIES
AMINES
ANIMALS
ANTICOAGULANTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY FLUIDS
CARBOHYDRATES
CARBOXYLIC ACID ESTERS
COBALT ISOTOPES
DOMESTIC ANIMALS
DRUGS
ESTERS
HEMATOLOGIC AGENTS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MATERIALS
METHACRYLIC ACID ESTERS
MINUTES LIVING RADIOISOTOPES
MUCOPOLYSACCHARIDES
NUCLEI
ODD-ODD NUCLEI
ORGANIC COMPOUNDS
ORGANIC POLYMERS
ORGANIC SULFUR COMPOUNDS
PETROCHEMICALS
PETROLEUM PRODUCTS
PLASTICS
POLYMERS
POLYOLEFINS
POLYSACCHARIDES
POLYVINYLS
RADIOISOTOPES
RUMINANTS
SACCHARIDES
SYNTHETIC MATERIALS
TESTING
VERTEBRATES
YEARS LIVING RADIOISOT
550601* - Medicine- Unsealed Radionuclides in Diagnostics