Absorption, retention, and utilization of two forms of selenium given simultaneously as stable isotope tracers to lactating and nonlactating women
Thesis/Dissertation
·
OSTI ID:6787274
We investigated absorption, retention, and utilization of selenomethionine (SeMet) and selenite (SeO{sub 3}) in 6 lactating and 6 nonlactating women, 2 to 3 mo postpartum, and 7 never pregnant women. Subjects were maintained on controlled diets for 3 wk. After 1 wk equilibration, subjects received simultaneous oral doses of {sup 74}Se L-SeMet and {sup 76}Se SeO{sub 3}. Complete urine and fecal collections were made for 1 d prior to and 2 wk after isotope dosing. Lactating women collected milk samples from all feedings for 24 h before and 48 h after isotopes. Blood was collected from subjects before isotope dosing and 2,24, 168, and 336 h later. All samples were analyzed for natural Se, {sup 74}Se, and {sup 76}Se by isotope dilution mass spectrometry.
- Research Organization:
- Maryland Univ., College Park, MD (USA)
- OSTI ID:
- 6787274
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550501 -- Metabolism-- Tracer Techniques
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ELEMENTS
EVEN-EVEN NUCLEI
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
ISOTOPE APPLICATIONS
ISOTOPE DILUTION
ISOTOPES
LACTATION
METABOLISM
NUCLEI
PREGNANCY
RETENTION
SELENIUM
SELENIUM 74
SELENIUM 76
SELENIUM ISOTOPES
SEMIMETALS
STABLE ISOTOPES
TRACER TECHNIQUES
UPTAKE
560300* -- Chemicals Metabolism & Toxicology
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ABSORPTION
ELEMENTS
EVEN-EVEN NUCLEI
INTERMEDIATE MASS NUCLEI
INTESTINAL ABSORPTION
ISOTOPE APPLICATIONS
ISOTOPE DILUTION
ISOTOPES
LACTATION
METABOLISM
NUCLEI
PREGNANCY
RETENTION
SELENIUM
SELENIUM 74
SELENIUM 76
SELENIUM ISOTOPES
SEMIMETALS
STABLE ISOTOPES
TRACER TECHNIQUES
UPTAKE