Thermographic studies of phantom and canine kidneys thawed by microwave radiation

Journal Article · Fri Jun 01 00:00:00 EDT 1990 · Cryobiology; (USA)

DOI:https://doi.org/10.1016/0011-2240(90)90030-8· OSTI ID:6787108

Schmehl, M K; Graham, E F; Kilkowski, S M ^[1]

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1. Univ. of Minnesota, St. Paul (USA)

Whole organs, such as kidneys, must be thawed quickly and uniformly to prevent damage during thawing due to excessive heating. Electromagnetic heating with microwaves thaws the kidneys quickly but frequently produces hot spots with heat damage. To study heat damage, phantom gelatin kidneys with different dielectric constants and canine kidneys perfused with 12.5% glycerol, ethylene glycol, or dimethyl sulfoxide before freezing were microwave thawed, and the interior temperature was measured by thermography. Phantom kidneys were thawed free standing and canine kidneys were either free standing or packed in a gel mixture. Both phantom and canine kidneys were split symmetrically and separated with a sheet of Styrofoam to facilitate immediate separation and evaluation of the halves after thawing (approximately 3 sec). All the phantoms, regardless of dielectric properties, had areas less than 0 degrees C or greater than 37 degrees C after thawing. The free-standing canine kidneys and the gel-packed ethylene glycol-perfused kidneys had frozen areas (less than 0 degrees C) and hot spots (greater than 37 degrees C). However, glycerol- and dimethyl sulfoxide-perfused kidneys packed in gel before thawing had no areas less than 0 degrees C or greater than 37 degrees C. Altering the geometry from a kidney shape to a cylindrical shape with increased volume improved the uniformity of thawing and was more effective than altering the dielectric constant over the range evaluated.

• OSTI ID: 6787108
• Journal Information: Cryobiology; (USA), Vol. 27:3; ISSN 0011-2240
• Country of Publication: United States
• Language: English

Related Subjects

63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
KIDNEYS
THAWING
MICROWAVE RADIATION
BIOLOGICAL EFFECTS
CRYOBIOLOGY
DOGS
PERFUSED ORGANS
PHANTOMS
ANIMALS
BIOLOGY
BODY
ELECTROMAGNETIC RADIATION
MAMMALS
MOCKUP
ORGANS
RADIATIONS
STRUCTURAL MODELS
VERTEBRATES
560400* - Other Environmental Pollutant Effects