Scintigraphic evaluation of childhood malignancies by /sup 67/Ga-citrate

Journal Article · Thu Jun 01 04:00:00 EDT 1978 · Radiology; (United States)

OSTI ID:6782387

Bekerman, C; Port, R B; Pang, E; Moohr, J W; Kranzler, J K

The utility and limitations of /sup 67/Ga scintigraphy in children with solid tumors were evaluated. Thirty-five patients with malignancies (13 lymphoreticular neoplasms, 11 soft-tissue sarcomas, 8 neuroblastomas, and 3 primary bone tumors) had a /sup 67/Ga-citrate scan as part of their clinical evaluation. The sensitivity and specificity of the test were analyzed for the different tumor types. The overall sensitivity of the /sup 67/Ga-citrate scan for the lymphoma group was 87%. Higher values were obtained for the mediastinal and abdominal regions. Ninety-three percent of the involved sites were correctly identified by /sup 67/Ga scintigraphy in the soft-tissue sarcoma group. Small lung metastases, however, were missed on scan. Thus, /sup 67/Ga scans should be complemented with chest radiographs and whole chest tomograms for both initial evaluation and follow-up in those patients. /sup 67/Ga had low sensitivity for neuroblastoma.

• Research Organization: Univ. of Chicago
• OSTI ID: 6782387
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 127:3; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BETA DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACID SALTS
CHILDREN
CITRATES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
GALLIUM 67
GALLIUM ISOTOPES
INFANTS
INTERMEDIATE MASS NUCLEI
ISOTOPES
LYMPHOMAS
MAMMALS
MAN
NEONATES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
PRIMATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SARCOMAS
SCINTISCANNING
SENSITIVITY
VERTEBRATES