The gallium scan in malignant fibrous histiocytoma

Conference · Sun Jan 01 04:00:00 EST 1984 · J. Nucl. Med.; (United States)

OSTI ID:6781120

Yeh, S D.J.; Rosen, G; Benua, R S

Soft tissue sarcoma is a relatively uncommon malignancy. Of its various histological types, malignant fibrous histiocytoma is most common and usually is seen in late adult life affecting primarily extremities and trunk with or without bony involvement. Before undertaking potentially toxic treatments with chemotherapeutic agents, tumor aggressiveness must be estimated. The authors use /sup 67/Ga citrate to supplement other imaging modalities to measure size, location and extent prior to and during treatment. In all, 22 consecutive patients were studied, with 13 males and 9 females. The median age was 43 (range 15 to 68) with majority of patients in 4th to 6th decades. Extremity lesions were present in 18, pelvic in 1, thoracic in 2, and abdominal in 1. Eighteen patients were studied shortly after the diagnosis and 4 during their recurrences. In the 18 patients with primary tumor, 12 showed marked increased uptake in the region of tumor, or increased uptake in soft tissues with a distribution different from the changes noted in the MDP bone scan. In 4 patients with extremity lesions, abnormalities were seen in Ga but were not definite in MDP bone scans. Four patients had tumor recurrences following surgery, radiation therapy or chemotherapy. High Ga uptake was found in the regions of recurrent tumor in 2 and in the lung metastases of another. Interval changes were more easily appreciated in the Ga scan than in the MDP bone scan. Information obtained from Ga images provides additional clues in determining extent of soft tissue involvement and assists in monitoring therapeutic responses.

• Research Organization: Memorial Sloan-Kettering Cancer Center, Cornell Medical College, New York, NY
• OSTI ID: 6781120
• Report Number(s): CONF-840619-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE DEPENDENCE
ANIMAL TISSUES
BETA DECAY RADIOISOTOPES
BODY
CARBOXYLIC ACID SALTS
CHEMOTHERAPY
CITRATES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
FEMALES
GALLIUM 67
GALLIUM ISOTOPES
IMAGE PROCESSING
IMAGES
INTERMEDIATE MASS NUCLEI
ISOTOPE APPLICATIONS
ISOTOPES
MALES
MEDICINE
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
PROCESSING
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SARCOMAS
SCINTISCANNING
SURGERY
THERAPY
TISSUES
TRACER TECHNIQUES
USES