Life shortening in mice exposed to fission neutrons and gamma rays. VI. Studies with the white-footed mouse, Peromyscus leucopus

Journal Article · Sat Nov 01 04:00:00 EST 1986 · Radiat. Res.; (United States)

DOI:https://doi.org/10.2307/3576823· OSTI ID:6776069

Thomson, J F; Williamson, F S; Grahn, D

Some of the studies on late effects of neutron and gamma radiation previously carried out with the C57BL6 X BALB/c F1 hybrids of Mus musculus have been repeated with the white-footed mouse, Peromyscus leucopus, a cricetid rodent of a different subfamily, with differing physiological characteristics and a different spectrum of pathologies. Among the more important findings were the following: For both species, the life shortening per rad at low doses of either radiation was the same percentage of the life span. The limiting values of the relative biological effectiveness for life shortening from all causes of death were about the same for the two species, ranging from 8 to 16, depending on the method of calculation. Fractionated neutron exposures failed to produce significant life shortening in Peromyscus over that observed at single doses. Tumor-related deaths accounted for at least 70 to 75% of the radiation-specific excess mortality in Peromyscus.

• Research Organization: Argonne National Lab., IL
• OSTI ID: 6776069
• Journal Information: Radiat. Res.; (United States), Journal Name: Radiat. Res.; (United States) Vol. 2; ISSN RAREA
• Country of Publication: United States
• Language: English

Related Subjects

560152* -- Radiation Effects on Animals-- Animals
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BARYONS
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
DELAYED RADIATION EFFECTS
DISEASES
ELECTROMAGNETIC RADIATION
ELEMENTARY PARTICLES
FERMIONS
FISSION NEUTRONS
GAMMA RADIATION
HADRONS
IONIZING RADIATIONS
LIFE SPAN
MAMMALS
MICE
NEOPLASMS
NEUTRONS
NUCLEONS
RADIATION EFFECTS
RADIATIONS
RBE
RODENTS
VERTEBRATES