Endometrial blood flow measured by xenon 133 clearance in women with normal menstrual cycles and dysfunctional uterine bleeding
Journal Article
·
· Am. J. Obstet. Gynecol.; (United States)
Endometrial blood flow was measured through the menstrual cycle in nonpregnant women (28 studies of 17 women with normal menstrual cycles and 32 studies of 20 women with dysfunctional uterine bleeding) with use of a clearance technique in which 100 to 400 microCi of the gamma-emitting isotope, xenon 133 in saline solution was instilled into the uterine cavity. The mean (+/- SEM) endometrial blood flow in normal cycles was 27.7 +/- 2.6 ml/100 gm/min, with a significant elevation in the middle to late follicular phase, followed by a substantial fall and a secondary slow luteal phase rise that was maintained until the onset of menstruation. There was a significant correlation between plasma estradiol levels and endometrial blood flow in the follicular but not the luteal phase. Blood flow patterns in women with ovulatory dysfunctional bleeding were similar to normal, except for a significantly lower middle follicular rate. Women with anovulatory dysfunctional bleeding exhibited exceedingly variable flow rates.
- Research Organization:
- Univ. of Sydney, New South Wales, Australia
- OSTI ID:
- 6775724
- Journal Information:
- Am. J. Obstet. Gynecol.; (United States), Journal Name: Am. J. Obstet. Gynecol.; (United States) Vol. 1; ISSN AJOGA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
560161* -- Radionuclide Effects
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD-PLASMA CLEARANCE
BODY
CLEARANCE
DAYS LIVING RADIOISOTOPES
ESTRADIOL
ESTRANES
ESTROGENS
EVEN-ODD NUCLEI
FEMALE GENITALS
FEMALES
HORMONES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MENSTRUAL CYCLE
MENSTRUATION DISORDERS
NUCLEI
ORGANIC COMPOUNDS
ORGANS
PRIMATES
RADIOISOTOPES
RADIONUCLIDE KINETICS
STEROID HORMONES
STEROIDS
UTERUS
VERTEBRATES
WOMEN
XENON 133
XENON ISOTOPES
Kinetics
& Toxicology-- Man
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD FLOW
BLOOD-PLASMA CLEARANCE
BODY
CLEARANCE
DAYS LIVING RADIOISOTOPES
ESTRADIOL
ESTRANES
ESTROGENS
EVEN-ODD NUCLEI
FEMALE GENITALS
FEMALES
HORMONES
HYDROXY COMPOUNDS
INTERMEDIATE MASS NUCLEI
INTERNAL CONVERSION RADIOISOTOPES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
MAMMALS
MAN
MENSTRUAL CYCLE
MENSTRUATION DISORDERS
NUCLEI
ORGANIC COMPOUNDS
ORGANS
PRIMATES
RADIOISOTOPES
RADIONUCLIDE KINETICS
STEROID HORMONES
STEROIDS
UTERUS
VERTEBRATES
WOMEN
XENON 133
XENON ISOTOPES