Acetyl coenzyme A synthetase catalyzed reactions of coenzyme A with. cap alpha. -. beta. -unsaturated carboxylic acids
Journal Article
·
· Anal. Biochem.; (United States)
..cap alpha..,..beta..-Unsaturated coenzyme A(CoA) thioesters including acrylyl CoA, methacrylyl CoA, and propiolyl CoA were synthesized by catalysis with acetyl CoA synthetase. After isolation from the enzymatic reactions, the products were found to be the result of 1,4 addition of CoASH to the double bond and addition of water to the triple bond of the initial acyl CoA adducts. Structural determinations of these products by /sup 1/H NMR, /sup 13/C NMR, and the chemical reaction leading to their formation are described.
- Research Organization:
- Tufts Univ., Medford, MA (USA)
- OSTI ID:
- 6768333
- Journal Information:
- Anal. Biochem.; (United States), Journal Name: Anal. Biochem.; (United States) Vol. 170:2; ISSN ANBCA
- Country of Publication:
- United States
- Language:
- English
Similar Records
New spectrophotometric and radiochemical assays for acetyl-CoA: arylamine N-acetyltransferase applicable to a variety of arylamines
Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase
The structure of S . lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain
Journal Article
·
Thu Feb 28 23:00:00 EST 1985
· Anal. Biochem.; (United States)
·
OSTI ID:5253617
Biochemical and Crystallographic Analysis of Substrate Binding and Conformational Changes in Acetyl-CoA Synthetase
Journal Article
·
Sun Dec 31 23:00:00 EST 2006
· Biochemistry
·
OSTI ID:930426
The structure of S . lividans acetoacetyl-CoA synthetase shows a novel interaction between the C-terminal extension and the N-terminal domain
Journal Article
·
Mon Dec 08 19:00:00 EST 2014
· Proteins
·
OSTI ID:1343103
Related Subjects
550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BARYONS
CARBON 13
CARBON ISOTOPES
CATALYSIS
COENZYMES
ELEMENTARY PARTICLES
ENZYMES
EVEN-ODD NUCLEI
FERMIONS
HADRONS
ISOTOPES
LIGASES
LIGHT NUCLEI
MAGNETIC RESONANCE
NUCLEAR MAGNETIC RESONANCE
NUCLEI
NUCLEONS
PROTONS
RESONANCE
STABLE ISOTOPES
62 RADIOLOGY AND NUCLEAR MEDICINE
BARYONS
CARBON 13
CARBON ISOTOPES
CATALYSIS
COENZYMES
ELEMENTARY PARTICLES
ENZYMES
EVEN-ODD NUCLEI
FERMIONS
HADRONS
ISOTOPES
LIGASES
LIGHT NUCLEI
MAGNETIC RESONANCE
NUCLEAR MAGNETIC RESONANCE
NUCLEI
NUCLEONS
PROTONS
RESONANCE
STABLE ISOTOPES