Division of Biological and Medical Research annual technical report, 1981

Technical Report · Tue Jun 01 00:00:00 EDT 1982

DOI:https://doi.org/10.2172/6757349· OSTI ID:6757349

Rosenthal, M W ^[1]

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1. ed.

This report summarizes research during 1981 in the Division of Biological and Medical Research, Argonne National Laboratory. Studies in Low Level Radiation include comparison of lifetime effects in mice of low level neutron and gamma irradiation, delineation of the responses of dogs to continuous low level gamma irradiation, elucidation of mechanisms of radiation damage and repair in mammalian cells, and study of the genetic effects of high LET radiations. Carcinogenesis research addresses mechanisms of tumor initiation and promotion in rat liver, chemical carcinogenesis in cultured mammalian cells, and molecular and genetic mechanisms of chemical and ultraviolet mutagenesis in bacteria. Research in Toxicology uses a variety of cellular, whole animal, and chronobiological end points, chemical separations, and statistical models to evaluate the hazards and mechanisms of actions of metals, coal gasification by products, and other energy-related pollutants. Human Protein Index studies develop two-dimensional electrophoresis systems for diagnosis and detection of cancer and other disease. Biophysics research includes fundamental structural and biophysical investigations of immunoglobulins and key biological molecules using NMR, crystallographic, and x-ray and neutron small-angle scattering techniques. The final sections cover support facilities, educational activities, seminars, staff talks, staff, and funding agencies.

• Research Organization: Argonne National Lab., IL (USA)
• DOE Contract Number: W-31109-ENG-38
• OSTI ID: 6757349
• Report Number(s): ANL-82-35; ON: DE83000920
• Country of Publication: United States
• Language: English

Related Subjects

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560121 -- Radiation Effects on Cells-- External Source-- (-1987)
560152* -- Radiation Effects on Animals-- Animals
560305 -- Chemicals Metabolism & Toxicology-- Vertebrates-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
ANL
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BIOLOGICAL RECOVERY
BIOLOGICAL REPAIR
BIOPHYSICS
CARBONACEOUS MATERIALS
CARCINOGENESIS
CELL CULTURES
COAL
COAL LIQUIDS
DOGS
ELECTROPHORESIS
ELEMENTS
ENERGY SOURCES
ENERGY TRANSFER
FLUIDS
FOSSIL FUELS
FUELS
GLOBULINS
IMMUNOGLOBULINS
IRRADIATION
LET
LIQUIDS
LOW DOSE IRRADIATION
MAMMALS
MAN
MATERIALS
METALS
MICE
MOLECULAR STRUCTURE
MUTAGENESIS
NATIONAL ORGANIZATIONS
ORGANIC COMPOUNDS
PATHOGENESIS
PRIMATES
PROTEINS
RADIATION EFFECTS
RECOVERY
REPAIR
RESEARCH PROGRAMS
RODENTS
TOXICITY
US AEC
US DOE
US ERDA
US ORGANIZATIONS
VERTEBRATES