Dietary accumulation and depuration of hydrophobic organochlorines: Bioaccumulation parameters and their relationship with the octanol/water partition coefficient

Journal Article · Thu Jan 01 04:00:00 EST 1998 · Environmental Toxicology and Chemistry

DOI:https://doi.org/10.1002/etc.5620170526· OSTI ID:675494

Fisk, A T ^[1]; Norstrom, R J ^[2]; Cymbalisty, C D; Muir, D C.G. ^[3]

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1. Univ. of Manitoba, Winnipeg, Manitoba (Canada). Dept. of Soil Science
2. Environment Canada, Hull, Quebec (Canada). National Wildlife Research Center
3. Dept. of Fisheries and Oceans, Winnipeg, Manitoba (Canada). Freshwater Inst.

Dietary accumulation of 23 hydrophobic organochlorines (OCs) by juvenile rainbow trout (Oncorhynchus mykiss) was studied with the objective of obtaining relationships between bioaccumulation parameters and the octanol/water partition coefficient (K{sub ow}). A wide range of OCs were used including 16 polychlorinated biphenyls, hexachlorobenzene, mirex, tris(4-chlorophenyl)methane (TCPMe), tris(4-chlorophenyl)methanol (TCPMeOH), and three toxaphene congeners. With the exception of TCPMeOH, Cl{sub 7}-CHB, and PCB 18, all of the OCs had biomagnification factors (BMFs) >1, implying a potential to biomagnify. Half-lives had a significant curvilinear relationship with K{sub ow} (R{sup 2} = 0.85, p < 0.001), with a maximum t{sub 1/2} for OCs with log K{sub ow} {approximately}7.0. Decreasing t{sub 1/2} for OCs of log K{sub ow} > 7.0 may be related to slow kinetics of these super hydrophobic OCs and the short exposure phase, which results in insufficient time for the super hydrophobic OCs to reach slower clearing compartments of the rainbow trout. Assimilation efficiency was not as well described by K{sub ow} as by t{sub 1/2} and BMF, although a significant curvilinear relationship was observed (R{sup 2} = 0.53, p = 0.004). The BMF had a significant curvilinear relationship with K{sub ow} (R{sup 2} = 0.84, p < 0.001). Recalcitrant OCs with a log K{sub ow} of {approximately}7.0 would appear to have the greatest potential for food chain biomagnification in fish.

• Sponsoring Organization: USDOE
• OSTI ID: 675494
• Journal Information: Environmental Toxicology and Chemistry, Journal Name: Environmental Toxicology and Chemistry Journal Issue: 1 Vol. 17; ISSN ETOCDK; ISSN 0730-7268
• Country of Publication: United States
• Language: English

Related Subjects

54 ENVIRONMENTAL SCIENCES
56 BIOLOGY AND MEDICINE
APPLIED STUDIES
BIOLOGICAL ACCUMULATION
BIOLOGICAL INDICATORS
CHLORINATED ALIPHATIC HYDROCARBONS
CHLORINATED AROMATIC HYDROCARBONS
POLYCHLORINATED BIPHENYLS
TROUT
WATER POLLUTION