Radionuclide plethysmography and Tc-99m red blood cell venography in venous thrombosis: comparison with contrast venography

Journal Article · Sun Jan 01 04:00:00 EST 1984 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.150.1.6689764· OSTI ID:6749518

Singer, I; Royal, H D; Uren, R F; Waugh, R C; McLaughlin, A F; Bautovich, G J; Dyer, I A; Fulton, R R; Morris, J G

Radionuclide plethysmography (RPG) is a new technique that uses Tc-99m labelled red blood cells to ascertain changes in venous volumes by detecting the change in counts in response to the inflation and deflation of proximal thigh cuffs. Diagnosis of ileofemoral venous occlusion is possible using this technique, which also provides kinetic data of venous outflow. A range of normal values was defined in 19 subjects for per cent change in venous capacitance and venous outflow. Twenty-one patients with suspected deep venous thrombosis were studied prospectively using RPG, radionuclide venography (RV), and contrast venography (CV) to establish the usefulness of RPG alone and in combination with RV in the diagnosis of deep venous thrombosis. RPG proved to be a reliable technique for the diagnosis of ileofemoral venous thrombosis (sensitivity, 91%; specificity, 100%). RV was less sensitive (73%) and less specific (93%) in diagnosing that condition. When RPG is used as the criterion for the detection of ileofemoral vein thrombosis and RV is used as the criterion for the detection of calf vein thrombosis, the combined techniques show improved sensitivity (92%) and specificity (93%) for the detection of all deep venous thromboses.

• Research Organization: Royal Prince Alfred Hospital, Camperdown, Australia
• OSTI ID: 6749518
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 150:1; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

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62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BIOMEDICAL RADIOGRAPHY
BLOOD
BLOOD CELLS
BLOOD FLOW
BLOOD VESSELS
BODY
BODY FLUIDS
CARDIOVASCULAR DISEASES
CARDIOVASCULAR SYSTEM
COMPARATIVE EVALUATIONS
COUNTING TECHNIQUES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
ERYTHROCYTES
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LABELLED COMPOUNDS
MATERIALS
MEDICINE
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
RADIOLOGY
TECHNETIUM 99
TECHNETIUM ISOTOPES
THROMBOSIS
VASCULAR DISEASES
VEINS
YEARS LIVING RADIOISOTOPES