Functional asplenia and portal hypertension in a patient with primary splenic hemangiosarcoma

Journal Article · Tue May 01 04:00:00 EDT 1990 · Clinical Nuclear Medicine; (USA)

DOI:https://doi.org/10.1097/00003072-199005000-00010· OSTI ID:6749394

Yuecel, A E.D.; Durak, H; Bernay, I; Bayraktar, Y; Bekdik, C; Telatar, H ^[1]

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1. Hacettepe Univ., Ankara (Turkey)

A 60-year-old man with primary splenic hemangiosarcoma (PSH) presented with weakness, weight loss, abdominal pain, and anemia. Physical examination revealed hepatomegaly, ascites, and firm, huge splenomegaly. Ultrasonography showed many nodular structures characterized by hypoechogenic and hyperechogenic areas. The patient also had portal hypertension, which was confirmed by physical findings and by measurement of portal vein pressure during operation. A liver-spleen scan using Tc-99m sulfur colloid and Tc-99m labeled heat denatured erythrocytes failed to demonstrate any splenic uptake, a reliable feature of functional asplenia. Although on a total body scan with Ga-67 citrate there was no splenic uptake, there was gallium uptake in the liver, where the presence of the metastatic lesion was histopathologically verified and confirmed by operation. There was also uptake in the middle zones of the lungs. Ga-67 citrate imaging appears to be helpful in the diagnosis of metastasis of PSH, and PSH can rarely cause portal hypertension.

• OSTI ID: 6749394
• Journal Information: Clinical Nuclear Medicine; (USA), Journal Name: Clinical Nuclear Medicine; (USA) Vol. 15:5; ISSN CNMED; ISSN 0363-9762
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARBOXYLIC ACID SALTS
CARDIOVASCULAR DISEASES
CITRATES
COLLOIDS
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIGESTIVE SYSTEM
DISEASES
DISPERSIONS
ELECTRON CAPTURE RADIOISOTOPES
ERYTHROCYTES
GALLIUM 67
GALLIUM ISOTOPES
GLANDS
HOURS LIVING RADIOISOTOPES
HYPERTENSION
INTERMEDIATE MASS NUCLEI
ISOMERIC NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIVER
MAMMALS
MAN
MATERIALS
METASTASES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
PRIMATES
RADIOISOTOPE SCANNING
RADIOISOTOPES
SARCOMAS
SPLEEN
SYMPTOMS
TECHNETIUM 99
TECHNETIUM ISOTOPES
ULTRASONOGRAPHY
VASCULAR DISEASES
VERTEBRATES
YEARS LIVING RADIOISOTOPES