Human brain mapping: Experimental and computational approaches
- Los Alamos National Lab., NM (US)
- Albuquerque VA Medical Center, NM (US)
- Massachusetts General Hospital, Boston, MA (US)
This is the final report of a three-year, Laboratory-Directed Research and Development (LDRD) project at the Los Alamos National Laboratory (LANL). This program developed project combined Los Alamos' and collaborators' strengths in noninvasive brain imaging and high performance computing to develop potential contributions to the multi-agency Human Brain Project led by the National Institute of Mental Health. The experimental component of the project emphasized the optimization of spatial and temporal resolution of functional brain imaging by combining: (a) structural MRI measurements of brain anatomy; (b) functional MRI measurements of blood flow and oxygenation; and (c) MEG measurements of time-resolved neuronal population currents. The computational component of the project emphasized development of a high-resolution 3-D volumetric model of the brain based on anatomical MRI, in which structural and functional information from multiple imaging modalities can be integrated into a single computational framework for modeling, visualization, and database representation.
- Research Organization:
- Los Alamos National Lab., NM (US)
- Sponsoring Organization:
- USDOE Assistant Secretary for Management and Administration, Washington, DC (US)
- DOE Contract Number:
- W-7405-ENG-36
- OSTI ID:
- 674923
- Report Number(s):
- LA-UR--98-2097; ON: DE99000815
- Country of Publication:
- United States
- Language:
- English
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