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Absolute left ventricular volume by an iterative build-up factor analysis of gated radionuclide images

Journal Article · · Radiology; (United States)
A method for determining absolute left ventricular (LV) volumes from radionuclide gated blood-pool (GBP) images was validated in 34 patients. The technique is nongeometric, corrects for tissue attenuation, and uses an experimentally determined set of build-up factors to account for the effects of scatter. Only four parameters are needed to determine LV volumes: the LV count rates from a left anterior oblique (LAO) and a right posterior oblique (RPO) image (180/sup 0/ opposed to the LAO), a venous blood sample, and a patient thickness measurement. A computer algorithm is used to reach an iterative solution to two simultaneous equations that yield LV volumes. Phantom studies showed less than 4% error for volume determinations at all investigated depths. For the patients studied the correlation between volumes obtained by GBP contrast ventriculography was 0.97 for diastole and 0.96 for systole.
Research Organization:
Temple Univ. Hospital, Philadelphia, PA
OSTI ID:
6747193
Journal Information:
Radiology; (United States), Journal Name: Radiology; (United States) Vol. 151:2; ISSN RADLA
Country of Publication:
United States
Language:
English