Early changes in gluconeogenesis and lipogenesis following destruction of the ventromedial hypothalamic nuclei
Journal Article
·
· Metabolism; (United States)
Young male rats were injected with tritiated water 6 h after destruction of the ventromedial hypothalamic nuclei (VMN). One hour later they were sacrificed and the incorporation of tritium into liver and carcass lipids, proteins, and glycogen and into plasma glucose and proteins was measured. It was found that lesioned rats showed increased incorporation into carcass and liver lipid, liver and plasma protein and plasma glucose. Conclusions are that the processes of lipogenesis and gluconeogenesis are accelerated within 6 h after VMN destruction.
- Research Organization:
- Veterans Administration Hospital, Buffalo, NY
- OSTI ID:
- 6741755
- Journal Information:
- Metabolism; (United States), Journal Name: Metabolism; (United States) Vol. 27:12; ISSN MTBMA
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
550201 -- Biochemistry-- Tracer Techniques
550501* -- Metabolism-- Tracer Techniques
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALDEHYDES
ANIMALS
BIOLOGICAL FUNCTIONS
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY
BODY FLUIDS
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
CHALCOGENIDES
DIGESTIVE SYSTEM
FUNCTIONS
GLANDS
GLUCOSE
GLYCOGEN
HEXOSES
HYPOTHALAMUS
LABELLED COMPOUNDS
LIPIDS
LIVER
MAMMALS
MATERIALS
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
OXIDES
OXYGEN COMPOUNDS
POLYSACCHARIDES
PROTEINS
RATS
RODENTS
SACCHARIDES
TRITIUM COMPOUNDS
TRITIUM OXIDES
VERTEBRATES
550501* -- Metabolism-- Tracer Techniques
551001 -- Physiological Systems-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
ALDEHYDES
ANIMALS
BIOLOGICAL FUNCTIONS
BIOLOGICAL MATERIALS
BLOOD
BLOOD PLASMA
BODY
BODY FLUIDS
BRAIN
CARBOHYDRATES
CENTRAL NERVOUS SYSTEM
CHALCOGENIDES
DIGESTIVE SYSTEM
FUNCTIONS
GLANDS
GLUCOSE
GLYCOGEN
HEXOSES
HYPOTHALAMUS
LABELLED COMPOUNDS
LIPIDS
LIVER
MAMMALS
MATERIALS
METABOLISM
MONOSACCHARIDES
NERVOUS SYSTEM
ORGANIC COMPOUNDS
ORGANS
OXIDES
OXYGEN COMPOUNDS
POLYSACCHARIDES
PROTEINS
RATS
RODENTS
SACCHARIDES
TRITIUM COMPOUNDS
TRITIUM OXIDES
VERTEBRATES