Recurrent medulloblastoma: Frequency of tumor enhancement on Gd-DTPA MR imaging

Journal Article · Tue May 01 00:00:00 EDT 1990 · AJNR, American Journal of Neuroradiology; (USA)

DOI:https://doi.org/10.2214/ajr.155.1.2112838· OSTI ID:6717378

Rollins, N; Mendelsohn, D; Mulne, A; Barton, R; Diehl, J; Reyes, N; Sklar, F ^[1]

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1. Children's Medical Center, Dallas, TX (USA)

Thirty-two children with medulloblastoma were evaluated postoperatively with conventional and gadolinium-enhanced MR imaging. Eleven patients had abnormal cranial MR studies; nine of these had recurrent tumor. In six patients recurrent tumor enhanced with Gd, while in the other three patients recurrent tumor did not enhance. The remaining two patients had areas of abnormal Gd enhancement that were caused by radiation-induced breakdown of the blood-brain barrier rather than by recurrent tumor. This study shows that not all recurrent medulloblastoma enhances and that the absence of Gd enhancement does not necessarily indicate the absence of recurrent tumor.

• OSTI ID: 6717378
• Journal Information: AJNR, American Journal of Neuroradiology; (USA), Journal Name: AJNR, American Journal of Neuroradiology; (USA) Vol. 11:3; ISSN 0195-6108; ISSN AAJND
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AGE GROUPS
AMINO ACIDS
BLOOD-BRAIN BARRIER
BODY
BRAIN
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
CHELATING AGENTS
CHILDREN
CONTRAST MEDIA
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
DTPA
GADOLINIUM ISOTOPES
ISOTOPES
MAGNETIC RESONANCE
NEOPLASMS
NERVOUS SYSTEM
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
RADIOPROTECTIVE SUBSTANCES
RARE EARTH ISOTOPES
RESONANCE