Localization of the human poly(A)-binding protein gene (PAB1) to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13 by in situ hybridization
Journal Article
·
· Genomics; (United States)
- Univ. of Otago, Christchurch (New Zealand)
A cDNA clone encoding the human poladenylate-binding protein (PABP) was isolated and mapped to the genome by in situ hybridization. The CDNA was found to bind preferentially to chromosomal regions 3q22-q25, 12q13-q14, and 13q12-q13. In addition, Southern blot analysis of genomic DNA using a PABP cDNA probe revealed a complex pattern of bands. The results indicate that PABP belongs to a multigene family of related sequences. 8 refs., 2 figs.
- OSTI ID:
- 6717136
- Journal Information:
- Genomics; (United States), Journal Name: Genomics; (United States) Vol. 15:1; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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