Radiotherapy of lymph node metastases in patients with squamous cell carcinoma of the head and neck region

Journal Article · Tue Jun 01 04:00:00 EDT 1982 · Int. J. Radiat. Oncol., Biol. Phys.; (United States)

DOI:https://doi.org/10.1016/0360-3016(82)90165-1· OSTI ID:6716833

Bartelink, H; Breur, K; Hart, G

The results of radiotherapy alone in 233 patients with lymph node metastases of squamous cell carcinoma in the head and neck region were examined. It appeared that the recurrence rate in the neck was mainly related to: localization of the primary tumor; the recurrence of the primary tumor; the radiation dose; and the presence of a residual palpable tumor mass in the neck 6 weeks after radiation. The optimum radiation dose was about 2000 ret. An isoeffect curve was calculated, which differed only slightly with the nominal standard dose (NSD) formula. Elective irradiation of the contralateral neck appeared to diminish the outgrowth of neck node metastases at that side. Changes in the radiation treatment in the last treatment period, such as a higher radiation dose and larger treatment area, resulted in a lower recurrence rate for the neck node metastases, and also in a higher survival rate.

• Research Organization: Netherlands Cancer Institute, Amsterdam, Netherlands
• OSTI ID: 6716833
• Journal Information: Int. J. Radiat. Oncol., Biol. Phys.; (United States), Journal Name: Int. J. Radiat. Oncol., Biol. Phys.; (United States) Vol. 8:6; ISSN IOBPD
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
BODY AREAS
CARCINOMAS
DIGESTIVE SYSTEM
DISEASES
DOSES
EVALUATION
HEAD
ISODOSE CURVES
LARYNX
LYMPH NODES
LYMPHATIC SYSTEM
MEDICINE
METASTASES
NECK
NEOPLASMS
NUCLEAR MEDICINE
ORGANS
PATIENTS
PHARYNX
RADIATION DOSES
RADIATION EFFECTS
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
THERAPY