Recurrent medulloblastoma: Frequency of tumor enhancement on Gd-DTPA MR imaging

Journal Article · Sun Jul 01 00:00:00 EDT 1990 · AJR, American Journal of Roentgenology; (USA)

DOI:https://doi.org/10.2214/ajr.155.1.2112838· OSTI ID:6707291

Rollins, N; Mendelsohn, D; Mulne, A; Barton, R; Diehl, J; Reyes, N; Sklar, F ^[1]

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1. Children's Medical Center, Dallas, TX (USA)

Thirty-two children with medulloblastoma were evaluated postoperatively with conventional and gadolinium-enhanced MR imaging. Eleven patients had abnormal cranial MR studies; nine of these had recurrent tumor. In six patients recurrent tumor enhanced with Gd, while in the other three patients recurrent tumor did not enhance. The remaining two patients had areas of abnormal Gd enhancement that were caused by radiation-induced breakdown of the blood-brain barrier rather than by recurrent tumor. This study shows that not all recurrent medulloblastoma enhances and that the absence of Gd enhancement does not necessarily indicate the absence of recurrent tumor.

• OSTI ID: 6707291
• Journal Information: AJR, American Journal of Roentgenology; (USA), Vol. 155:1; ISSN 0361-803X
• Country of Publication: United States
• Language: English

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62 RADIOLOGY AND NUCLEAR MEDICINE
BRAIN
NEOPLASMS
DIAGNOSIS
BLOOD-BRAIN BARRIER
CHILDREN
CONTRAST MEDIA
DTPA
NECROSIS
NMR IMAGING
NUCLEAR MAGNETIC RESONANCE
PATIENTS
AGE GROUPS
AMINO ACIDS
BODY
CARBOXYLIC ACIDS
CENTRAL NERVOUS SYSTEM
CHELATING AGENTS
DIAGNOSTIC TECHNIQUES
DISEASES
DRUGS
MAGNETIC RESONANCE
NERVOUS SYSTEM
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANS
PATHOLOGICAL CHANGES
RADIOPROTECTIVE SUBSTANCES
RESONANCE
550601* - Medicine- Unsealed Radionuclides in Diagnostics