NIOSH comments to DOL on occupational exposure to methylene chloride by R. W. Niemeier, April 6, 1992

Technical Report · Thu Jun 04 04:00:00 EDT 1992

OSTI ID:6702732

The testimony summarizes the views of NIOSH regarding the development of a more protective standard for exposure to methylene-chloride (75092). The permissible exposure limit was 500 parts per million (ppm) as a time weighted average (TWA). This was deemed to be to high and the suggestion was to lower that to a 25ppm TWA. Comments in the testimony concern pharmacokinetics, central nervous system health effects, epidemiology, medical surveillance, exposure monitoring, control technology, respiratory protection and other protective equipment. While the results of epidemiological studies have failed to demonstrate an excess risk of lung cancer, the findings are somewhat contradictory with respect to mortality from ischemic heart disease and liver cancer.

• Research Organization: National Inst. for Occupational Safety and Health, Cincinnati, OH (United States)
• OSTI ID: 6702732
• Report Number(s): PB-93-136208/XAB
• Country of Publication: United States
• Language: English

Related Subjects

560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BODY
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
CONTROL
DIGESTIVE SYSTEM
DISEASES
EPIDEMIOLOGY
EQUIPMENT
GLANDS
HEART
INDUSTRIAL MEDICINE
LIVER
MAXIMUM PERMISSIBLE EXPOSURE
MEDICAL SURVEILLANCE
MEDICINE
METHYLENE CHLORIDE
MONITORING
MORTALITY
NEOPLASMS
NERVOUS SYSTEM
OCCUPATIONAL EXPOSURE
OCCUPATIONAL SAFETY
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
ORGANS
RISK ASSESSMENT
SAFETY
SAFETY STANDARDS
STANDARDS
SURVEILLANCE
TOXICITY