Acute cytotoxicity of fossil-energy-related comparative research materials

Journal Article · Fri Jan 01 04:00:00 EST 1982 · J. Environ. Sci. Health, Part A; (United States)

DOI:https://doi.org/10.1080/10934528209375025· OSTI ID:6702728

Schultz, T W

Aqueous extracts of five fossil-energy-related comparative research materials have been examined under acute static conditions for toxic effects by use of the Tetrahymena assay system. Cells were exposed to various concentrations of extracts, and cytolysis and population growth impairment were monitored. In addition, chemical class fractionation and major organic elemental analysis were performed. Synthetic fossil fuel materials are more toxic than conventional petroleum crude oils and coal-derived materials are more toxic than crude shale oil. Synthetic fossil-fuel-related materials have a higher nitrogen and oxygen content and a greater aromaticity than do natural crude oils. Acute toxicity appears to be correlated with ether-soluble acid (phenolic) content, mono- and diaromatic hydrocarbon content, and ether-soluble base (primary aromatic amines and azaarenes) content.

• Research Organization: Oak Ridge National Lab., TN
• DOE Contract Number: W-7405-ENG-26
• OSTI ID: 6702728
• Journal Information: J. Environ. Sci. Health, Part A; (United States), Journal Name: J. Environ. Sci. Health, Part A; (United States) Vol. A17:2; ISSN JESED
• Country of Publication: United States
• Language: English

Related Subjects

560301* -- Chemicals Metabolism & Toxicology-- Cells-- (-1987)
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
ANIMAL CELLS
ANIMALS
AROMATICS
BIOASSAY
BIOLOGICAL EFFECTS
CELL KILLING
CHEMICAL ANALYSIS
CILIATA
ENERGY SOURCES
FOSSIL FUELS
FUELS
GROWTH
HYDROCARBONS
HYDROXY COMPOUNDS
INHIBITION
INVERTEBRATES
MICROORGANISMS
ORGANIC COMPOUNDS
PHENOLS
POLYCYCLIC AROMATIC HYDROCARBONS
PROTOZOA
QUALITATIVE CHEMICAL ANALYSIS
SOLUBILITY
TETRAHYMENA
TOXICITY