Choroidal melanoma: I-125 plaque therapy

Journal Article · Sat Oct 01 00:00:00 EDT 1988 · Radiology; (United States)

DOI:https://doi.org/10.1148/radiology.169.1.3420267· OSTI ID:6700659

Bosworth, J L; Packer, S; Rotman, M; Ho, T; Finger, P T

An iodine-125 eye plaque was used to treat 58 patients with choroidal melanoma. Patients were followed up for a mean of 48.7 months. Fifty patients had medium-sized lesions (height between 3.1 and 8.0 mm and base diameter less than 16.0 mm), and six patients had large lesions. There were 24 lesions less than 3.0 mm from the optic nerve. The average radiation dose to the apex of the tumor was 8,468 cGy (dose rate, 71 cGy per hour). Initial local disease control was achieved in 50 patients (86.2%). One patient with local treatment failure received another plaque treatment, which controlled disease, so the total disease control rate was 87.9%. Only eight patients died of their disease. Complications were similar to those with other treatment methods, but none of the patients in this study developed optic nerve atrophy.

• Research Organization: North Shore Univ. Hospital, Manhasset, NY (USA)
• OSTI ID: 6700659
• Journal Information: Radiology; (United States), Journal Name: Radiology; (United States) Vol. 169:1; ISSN RADLA
• Country of Publication: United States
• Language: English

Related Subjects

550603* -- Medicine-- External Radiation in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ELECTRON CAPTURE RADIOISOTOPES
EYES
FACE
HEAD
INTERMEDIATE MASS NUCLEI
IODINE 125
IODINE ISOTOPES
ISOTOPES
MEDICINE
MELANOMAS
NEOPLASMS
NUCLEAR MEDICINE
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIATION DOSES
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
SENSE ORGANS
THERAPY