Incidence of malignant thyroid tumors in humans after exposure to diagnostic doses of /sup 131/I. II. Estimation of thyroid gland size, thyroid radiation dose, and predicted versus observed number of malignant thyroid tumors

Journal Article · Mon Dec 01 04:00:00 EST 1980 · J. Natl. Cancer Inst.; (United States)

OSTI ID:6689933

Holm, L E ^[1]; Eklund, G; Lundell, G

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1. Karolinska Hospital, Stockholm, Sweden

The size of the thyroid glands was analyzed for 10% of the patients in a selected group that had been exposed to diagnostic doses of /sup 131/I. The mean thyroid gland weight +- SD was 50 +- 33 g for patients 20 or more years of age and 10 +- 5 g for patients less than 20 years of age. With the present follow-up, diagnostic doses of /sup 131/I appeared not to be associated with an increased risk for later development of malignant thyroid tumors. Possible reasons for the difference between the observed number of such tumors and the number expected (47 to 124) on the basis of risk estimates of the United Nations Scientific Committee on the Effects of Atomic Radiation are discussed.

• OSTI ID: 6689933
• Journal Information: J. Natl. Cancer Inst.; (United States), Journal Name: J. Natl. Cancer Inst.; (United States) Vol. 65:6; ISSN JNCIA
• Country of Publication: United States
• Language: English

Related Subjects

550600* -- Medicine
550900 -- Pathology
560151 -- Radiation Effects on Animals-- Man
59 BASIC BIOLOGICAL SCIENCES
62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
BODY
DAYS LIVING RADIOISOTOPES
DISEASES
DOSES
ENDOCRINE GLANDS
GLANDS
INTERMEDIATE MASS NUCLEI
INTERNATIONAL ORGANIZATIONS
IODINE 131
IODINE ISOTOPES
ISOTOPES
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
ORGANS
PATIENTS
RADIATION DOSES
RADIATION EFFECTS
RADIOISOTOPES
RISK ASSESSMENT
SIZE
THYROID
UNITED NATIONS
WEIGHT