Clinical comparison of cardiac blood pool visualization with technetium-99m red blood cells labeled in vivo and with technetium-99m human serum albumin

Journal Article · Sat Jul 01 00:00:00 EDT 1978 · J. Nucl. Med.; (United States)

OSTI ID:6688352

Thrall, J H; Freitas, J E; Swanson, D; Rogers, W L; Clare, J M; Brown, M L; Pitt, B

Technetium-99m red blood cells (Tc-RBC) labeled by an in vivo technique were compared with two preparations of Tc-99m human serum albumin (HSA) for cardiac blood-pool imaging. Relative distribution of the tracers was analyzed on end-diastolic frames of gated blood-pool studies and on whole-body (head to mid-thigh) anterior pinhole images. The Tc-RBC demonstrated greater relative percentage localization in the cardiac blood pool, higher target-to-background ratios in the left ventricle, and less liver concentration. For cardiac blood-pool imaging, Tc-RBC labeled by the in vivo approach appears to be superior to the two Tc-HSA preparations studied.

• Research Organization: Univ. of Michigan Medical Center, Ann Arbor, MI
• OSTI ID: 6688352
• Journal Information: J. Nucl. Med.; (United States), Vol. 19:7
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
ALBUMINS
RADIOPHARMACEUTICALS
BLOOD CIRCULATION
MEASURING METHODS
ERYTHROCYTES
LABELLING
HEART
SCINTISCANNING
BIOLOGICAL LOCALIZATION
COMPARATIVE EVALUATIONS
TECHNETIUM 99
BLOOD SERUM
IN VIVO
ISOMERIC NUCLEI
LABELLED COMPOUNDS
PATIENTS
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BIOLOGICAL MATERIALS
BLOOD
BLOOD CELLS
BODY
BODY FLUIDS
CARDIOVASCULAR SYSTEM
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DRUGS
HOURS LIVING RADIOISOTOPES
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
NUCLEI
ODD-EVEN NUCLEI
ORGANIC COMPOUNDS
ORGANS
PROTEINS
RADIOACTIVE MATERIALS
RADIOISOTOPE SCANNING
RADIOISOTOPES
TECHNETIUM ISOTOPES
YEARS LIVING RADIOISOTOPES
550601* - Medicine- Unsealed Radionuclides in Diagnostics