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Title: Serum thyroglobulin, a monitor of differentiated thyroid carcinoma in patients receiving thyroid hormone suppression therapy: concise communication

Journal Article · · J. Nucl. Med.; (United States)
OSTI ID:6682866

Serum thyroglobulin levels were obtained in 86 patients who had undergone thyroidectomy and I-131 ablation for differentiated thyroid cancer, and who were receiving or had recently discontinued thyroid hormone suppression therapy. Excellent correlation was observed between serum thyroglobulin levels in patients receiving thyroid hormone suppression therapy and I-131 imaging studies. Serum thyroglobulin levels equal to or below 20 ng/ml indicate the absence of thyroid carcinoma, and values exceeding 60 ng/ml were indicative of active thyroid cancer but may include some patients without clinical evidence of disease. Intermediate serum thyroglobulin levels were observed in a small number of patients with post-surgical thyroid remnants or active disease.

Research Organization:
Univ. of California, Los Angeles
OSTI ID:
6682866
Journal Information:
J. Nucl. Med.; (United States), Vol. 25:6
Country of Publication:
United States
Language:
English