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Title: Hot spot liver scan in focal nodular hyperplasia

Abstract

In scintigraphy of the liver with radiocolloid, space-occupying lesions generally are visualized as regions of decreased accumulation of radioactivity. Rarely focal areas of increased activity are depicted; most are related to altered vascular dynamics in the liver secondary to obstruction of the superior or inferior vena cava or the hepatic veins. There are reports of single cases of focally increased activity due to a hepatic hemangioma, hepatic venoocclusive disease, herniation of a part of the liver, and a liver hot spot found after radiocolloid injection via a malpositioned central venous catheter in one of the hepatic vein branches. In patients with focal nodular hyperplasia, liver scans with solitary defects as well as normal patterns are found. In some cases, increased uptake of colloid in the lesion has been documented. Pasquier and Dorta reported a patient with a palpable mass in the left liver lobe with increased accumulation of radioactivity on the radiocolloid liver scan. The histologic diagnosis was hamartoma, but reviewing the description and considering the confusion in the past concerning the nomenclature, this case is suggestive of focal nodular hyperplasia. We report a patient with focal nodular hyperplasia who had increased radiocolloid uptake in the lesion. The radionuclide studiesmore » are compared with angiography, sonography, and computed tomography. An explanation for the localized increased colloid accumulation based on histologic findings is suggested.« less

Authors:
 [1]; ; ; ; ;
  1. (Univ. Hospital, Groningen, Netherlands)
Publication Date:
OSTI Identifier:
6677198
Alternate Identifier(s):
OSTI ID: 6677198
Resource Type:
Journal Article
Resource Relation:
Journal Name: Am. J. Roentgenol.; (United States); Journal Volume: 135:6
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 59 BASIC BIOLOGICAL SCIENCES; LIVER; SCINTISCANNING; PATHOLOGICAL CHANGES; DIAGNOSIS; TECHNETIUM 99; DIAGNOSTIC USES; BIOLOGICAL LOCALIZATION; BLOOD VESSELS; ISOMERIC NUCLEI; PATIENTS; PERFUSED ORGANS; RADIOCOLLOIDS; RADIONUCLIDE KINETICS; SULFUR COMPLEXES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARDIOVASCULAR SYSTEM; COLLOIDS; COMPLEXES; COUNTING TECHNIQUES; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISPERSIONS; GLANDS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TECHNETIUM ISOTOPES; USES; YEARS LIVING RADIOISOTOPES 550601* -- Medicine-- Unsealed Radionuclides in Diagnostics; 551001 -- Physiological Systems-- Tracer Techniques

Citation Formats

Piers, D.A., Houthoff, H.J., Krom, R.A.F., Schuur, K.H., Sikkens, H., and Weits, J. Hot spot liver scan in focal nodular hyperplasia. United States: N. p., 1980. Web. doi:10.2214/ajr.135.6.1289.
Piers, D.A., Houthoff, H.J., Krom, R.A.F., Schuur, K.H., Sikkens, H., & Weits, J. Hot spot liver scan in focal nodular hyperplasia. United States. doi:10.2214/ajr.135.6.1289.
Piers, D.A., Houthoff, H.J., Krom, R.A.F., Schuur, K.H., Sikkens, H., and Weits, J. Mon . "Hot spot liver scan in focal nodular hyperplasia". United States. doi:10.2214/ajr.135.6.1289.
@article{osti_6677198,
title = {Hot spot liver scan in focal nodular hyperplasia},
author = {Piers, D.A. and Houthoff, H.J. and Krom, R.A.F. and Schuur, K.H. and Sikkens, H. and Weits, J.},
abstractNote = {In scintigraphy of the liver with radiocolloid, space-occupying lesions generally are visualized as regions of decreased accumulation of radioactivity. Rarely focal areas of increased activity are depicted; most are related to altered vascular dynamics in the liver secondary to obstruction of the superior or inferior vena cava or the hepatic veins. There are reports of single cases of focally increased activity due to a hepatic hemangioma, hepatic venoocclusive disease, herniation of a part of the liver, and a liver hot spot found after radiocolloid injection via a malpositioned central venous catheter in one of the hepatic vein branches. In patients with focal nodular hyperplasia, liver scans with solitary defects as well as normal patterns are found. In some cases, increased uptake of colloid in the lesion has been documented. Pasquier and Dorta reported a patient with a palpable mass in the left liver lobe with increased accumulation of radioactivity on the radiocolloid liver scan. The histologic diagnosis was hamartoma, but reviewing the description and considering the confusion in the past concerning the nomenclature, this case is suggestive of focal nodular hyperplasia. We report a patient with focal nodular hyperplasia who had increased radiocolloid uptake in the lesion. The radionuclide studies are compared with angiography, sonography, and computed tomography. An explanation for the localized increased colloid accumulation based on histologic findings is suggested.},
doi = {10.2214/ajr.135.6.1289},
journal = {Am. J. Roentgenol.; (United States)},
number = ,
volume = 135:6,
place = {United States},
year = {Mon Dec 01 00:00:00 EST 1980},
month = {Mon Dec 01 00:00:00 EST 1980}
}