Cosolvent-induced solubilization of hydrophobic compounds into water

Journal Article · Sat Oct 01 04:00:00 EDT 1988 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00170a034· OSTI ID:6668220

Banerjee, S; Yalkowsky, S H

The solubilization of toluene into water by propylene glycol and methanol was measured by a novel liquid chromatographic procedure. The relationship between solubilization and cosolvent content is linear up to 10-20 vol % of cosolvent, beyond which conventional logarithmic behavior is observed. The point of departure from linearity is believed to signal the onset of interaction between the extended hydration shells of the cosolvent. For propylene glycol, the volume of this shell is about 500 mL/mol, and the solubility of toluene within the shell is about 1.3 times its solubility in pure water.

• Research Organization: Brookhaven National Lab., Upton, NY (USA)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 6668220
• Journal Information: Anal. Chem.; (United States), Journal Name: Anal. Chem.; (United States) Vol. 60:19; ISSN ANCHA
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
400201* -- Chemical & Physicochemical Properties
ALCOHOLS
ALKYLATED AROMATICS
AROMATICS
CHROMATOGRAPHY
DATA
EXPERIMENTAL DATA
GLYCOLS
HYDROCARBONS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
INFORMATION
LIQUID COLUMN CHROMATOGRAPHY
METHANOL
NUMERICAL DATA
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
SEPARATION PROCESSES
SOLUBILITY
SOLVENT PROPERTIES
TOLUENE
WATER