Cosolvent-induced solubilization of hydrophobic compounds into water

Journal Article · Sat Oct 01 00:00:00 EDT 1988 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac00170a034· OSTI ID:6668220

Banerjee, S; Yalkowsky, S H

The solubilization of toluene into water by propylene glycol and methanol was measured by a novel liquid chromatographic procedure. The relationship between solubilization and cosolvent content is linear up to 10-20 vol % of cosolvent, beyond which conventional logarithmic behavior is observed. The point of departure from linearity is believed to signal the onset of interaction between the extended hydration shells of the cosolvent. For propylene glycol, the volume of this shell is about 500 mL/mol, and the solubility of toluene within the shell is about 1.3 times its solubility in pure water.

• Research Organization: Brookhaven National Lab., Upton, NY (USA)
• DOE Contract Number: AC02-76CH00016
• OSTI ID: 6668220
• Journal Information: Anal. Chem.; (United States), Vol. 60:19
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
GLYCOLS
SOLVENT PROPERTIES
METHANOL
TOLUENE
SOLUBILITY
WATER
EXPERIMENTAL DATA
LIQUID COLUMN CHROMATOGRAPHY
ALCOHOLS
ALKYLATED AROMATICS
AROMATICS
CHROMATOGRAPHY
DATA
HYDROCARBONS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
INFORMATION
NUMERICAL DATA
ORGANIC COMPOUNDS
OXYGEN COMPOUNDS
SEPARATION PROCESSES
400201* - Chemical & Physicochemical Properties