The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum
The overall objective of this project is to elucidate the detailed mechanism by which solvent-forming bacteria such as Clostridium acetobutylicum regulate the well-known shift in fermentation pathway between alcohol-acetone and organic acid production. It is desired to eventually isolate and describe: (1) the regulatory genes and protein elements that determine induction of synthesis of the solvent-pathway enzymes; and (2) how this regulation system interacts with the sporulatin induction and development program and with related pathways such as granulse and exopolysaccharide formation in clostridia. A working model forhow clostridial control systems work can be derived from recent research on stress systems in E. coli and sporulation in Bacillus subtilis.
- Research Organization:
- Minnesota Univ., Minneapolis, MN (United States). Medical School
- Sponsoring Organization:
- DOE; USDOE, Washington, DC (United States)
- DOE Contract Number:
- FG02-86ER13512
- OSTI ID:
- 6665868
- Report Number(s):
- DOE/ER/13512-T2; ON: DE93008396
- Country of Publication:
- United States
- Language:
- English
Similar Records
The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum. Technical progress report, July 1990--December 1992
The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum. Technical progress report, July 1990--June 1993
The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum
Technical Report
·
Wed Dec 30 23:00:00 EST 1992
·
OSTI ID:10128398
The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum. Technical progress report, July 1990--June 1993
Technical Report
·
Mon Oct 31 23:00:00 EST 1994
·
OSTI ID:10194921
The mechanism of switching from an acidogenic to butanol-acetone fermentation by Clostridium acetobutylicum
Technical Report
·
Mon Dec 31 23:00:00 EST 1990
·
OSTI ID:5879839
Related Subjects
09 BIOMASS FUELS
090900* -- Biomass Fuels-- Processing-- (1990-)
550200 -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ACETONE
ALCOHOLS
BACTERIA
BIOLOGICAL PATHWAYS
BIOTECHNOLOGY
CARBOXYLIC ACIDS
CLOSTRIDIUM
CLOSTRIDIUM ACETOBUTYLICUM
DNA
DOCUMENT TYPES
ETHANOL
GENE REGULATION
GENETIC ENGINEERING
HYDROXY COMPOUNDS
KETONES
METHANOGENIC BACTERIA
MICROORGANISMS
MONOCARBOXYLIC ACIDS
NUCLEIC ACIDS
OLIGONUCLEOTIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
PROGRESS REPORT
RECOMBINANT DNA
TRANSPOSONS
090900* -- Biomass Fuels-- Processing-- (1990-)
550200 -- Biochemistry
59 BASIC BIOLOGICAL SCIENCES
ACETONE
ALCOHOLS
BACTERIA
BIOLOGICAL PATHWAYS
BIOTECHNOLOGY
CARBOXYLIC ACIDS
CLOSTRIDIUM
CLOSTRIDIUM ACETOBUTYLICUM
DNA
DOCUMENT TYPES
ETHANOL
GENE REGULATION
GENETIC ENGINEERING
HYDROXY COMPOUNDS
KETONES
METHANOGENIC BACTERIA
MICROORGANISMS
MONOCARBOXYLIC ACIDS
NUCLEIC ACIDS
OLIGONUCLEOTIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
PROGRESS REPORT
RECOMBINANT DNA
TRANSPOSONS