Assignment of fifty-four cosmid clones to five regions of chromosome 10
Journal Article
·
· Genomics; (United States)
- Univ. of Cambridge (United Kingdom)
- Cancer Inst., Tokyo (Japan)
The gene implicated in the development of multiple endocrine neoplasia type 2A, and inherited cancer syndrome transmitted as an autosomal dominant trait, has been mapped by genetic linkage to the pericentromeric region of chromosome 10. To isolate new markers for this region, we constructed cosmid libraries from two radiation hybrids, R104-2D2 and R244-3A1, derived from the hybrid cell line 762-8A, which contains only human chromosomes 10 and Y in a hamster background. 15 refs., 1 tab.
- OSTI ID:
- 6660044
- Journal Information:
- Genomics; (United States), Journal Name: Genomics; (United States) Vol. 15:2; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
Similar Records
Isolation of region-specific cosmids by hybridization with microdissection clones from human chromosome 10q11. 1-q21. 1
Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs
Hereditary hyperparathyroidism-jaw tumor syndrome: the endocrine tumor gene HRPT2 maps to chromosome 1q21-q31
Journal Article
·
Sun Aug 01 00:00:00 EDT 1993
· Genomics; (United States)
·
OSTI ID:7009594
Improved predictive test for MEN2, using flanking dinucleotide repeats and RFLPs
Journal Article
·
Mon Nov 30 23:00:00 EST 1992
· American Journal of Human Genetics; (United States)
·
OSTI ID:6697606
Hereditary hyperparathyroidism-jaw tumor syndrome: the endocrine tumor gene HRPT2 maps to chromosome 1q21-q31
Journal Article
·
Fri Mar 31 23:00:00 EST 1995
· American Journal of Human Genetics
·
OSTI ID:70430