Hyperbaric oxygen therapy for laryngeal radionecrosis

Journal Article · Thu Jan 01 04:00:00 EST 1987 · Ann. Otol., Rhinol., Laryngol.; (United States)

DOI:https://doi.org/10.1177/000348948709600101· OSTI ID:6645948

Ferguson, B J; Hudson, W R; Farmer, Jr, J C

Radionecrosis of the larynx is a debilitating disease associated with pain, dysphagia, respiratory obstruction, and, in some cases, the need for laryngectomy. Persistent poor wound healing can lead to death. A series of eight patients with advanced (grades III and IV, Chandler classification) radionecrosis of the larynx treated with adjunctive hyperbaric oxygen therapy is presented. Signs and symptoms of radionecrosis were dramatically ameliorated in seven of eight patients, while one patient, despite subjective improvement, eventually required laryngectomy. There were no deaths. These results are compared to previous series on radionecrosis of the larynx in which hyperbaric oxygen was not used. This series indicates that hyperbaric oxygen therapy is a useful and effective adjunctive treatment modality in the management of laryngeal radionecrosis.

• Research Organization: Duke Univ. Medical Center, Durham, NC
• OSTI ID: 6645948
• Journal Information: Ann. Otol., Rhinol., Laryngol.; (United States), Journal Name: Ann. Otol., Rhinol., Laryngol.; (United States); ISSN AORHA
• Country of Publication: United States
• Language: English

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63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
BIOLOGICAL EFFECTS
BIOLOGICAL RADIATION EFFECTS
ELEMENTS
INJURIES
LARYNX
MEDICINE
NECROSIS
NONMETALS
NUCLEAR MEDICINE
OXYGEN
PATHOLOGICAL CHANGES
PATIENTS
POST-IRRADIATION THERAPY
RADIATION EFFECTS
RADIATION INJURIES
RADIOLOGY
RADIOTHERAPY
RESPIRATORY SYSTEM
SIDE EFFECTS
THERAPY