Comparison of Ga-67 planar imaging and single photon emission computed tomography in malignant chest disease

Conference · Wed May 01 04:00:00 EDT 1985 · J. Nucl. Med.; (United States)

OSTI ID:6639425

Tumeh, S S; Rosenthal, D; Kaplan, W D; English, R E; Holman, B L

To determine the value of Ga-67 single photon emission computed tomography (SPECT) in patients (pts) with malignant chest disease, the authors compared Ga-67 planar scans (ps) and SPECT with the medical records in twenty-five consecutive patients. Twenty-three examinations were performed on 17 pts with Hodgkin's disease (HD) and three pts with non-Hodgkin's lymphoma. Five examinations were performed on 5 pts with bronchogenic carcinoma (BC). The two modalities were evaluated for (1) presence or absence of disease, (2) number of foci of abnormal uptake and (3) extent of disease. In pts with lymphoma, SPECT defined the extent of disease better than planar imaging in eight examinations; it demonstrated para-cardial involvement in one pt, separated hilar from mediastinal disease in 4, and demonstrated posterior mediastinal disease in 3. SPECT clarified suspicious foci on planar images in seven examinations, correctly ruled out disease in two pts with equivocal planar images and did not exchange planar image findings in six examinations. In pts with bronchogenic carcinoma, both medalities correctly ruled out mediastinal involvement in three pts. SPECT detected mediastinal lymph node involvement in one pt with equivocal planar images. Both SPECT and planar imaging missed direct tumor extension to the mediastinum in one pt. They conclude that Ga-67 with SPECT is better than planar images for staging of chest lymphoma and BC. Since it defines different lymph node groups it carries a good potential for staging as well as follow up of those pts.

• Research Organization: Departments of Radiology and Medicine, Harvard Medical School, Boston, MA
• OSTI ID: 6639425
• Report Number(s): CONF-850611-
• Conference Information: Journal Name: J. Nucl. Med.; (United States) Journal Volume: 26:5
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BODY
BODY AREAS
CARCINOMAS
CHEST
COMPARATIVE EVALUATIONS
COMPUTERIZED TOMOGRAPHY
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
EMISSION COMPUTED TOMOGRAPHY
GALLIUM 67
GALLIUM ISOTOPES
IMAGES
INTERMEDIATE MASS NUCLEI
ISOTOPES
LYMPHOMAS
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
PERFORMANCE
RADIOISOTOPE SCANNING
RADIOISOTOPES
RESPIRATORY SYSTEM DISEASES
SINGLE PHOTON EMISSION COMPUTED TOMOGRAPHY
TOMOGRAPHY
USES