Sutureless vascular end-to-end anastomosis. Final technical report Jan 82-Dec 83

Technical Report · Thu Mar 22 00:00:00 EST 1984

OSTI ID:6627802

Wozniak, J J

The objective of this project was to develop a means of rejoining severed vessels (end-to-end anastomosis) without using sutures. Two essential elements in the concept, an instrument to evert the vessel and a biocompatible, low-temperature (130 F/54 C), heat-shrinkage sleeve were developed. The sleeve, which contracts to accomplish the anastomosis, was developed by crosslinking (with ionizing gamma radiation) synthetic trans-1,4 polyisoprene. The crosslinked polymer was subjected to an acute toxicity screening program and proved to be highly biocompatible. The sutureless anastomosis technique was tested in-vitro on freshly excised pig carotid arteries however, there was insufficient funding available to provide for an evaluation of the technique in laboratory animals.

• Research Organization: Johns Hopkins Univ., Laurel, MD (USA). Applied Physics Lab.
• OSTI ID: 6627802
• Report Number(s): AD-A-140484/7
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
BLOOD VESSELS
JOINING
POLYISOPRENE
CROSS-LINKING
SLEEVES
COMPATIBILITY
GAMMA RADIATION
MEDIUM TEMPERATURE
SWINE
ANIMALS
BODY
CARDIOVASCULAR SYSTEM
CHEMICAL REACTIONS
DOMESTIC ANIMALS
ELASTOMERS
ELECTROMAGNETIC RADIATION
FABRICATION
IONIZING RADIATIONS
MAMMALS
ORGANIC COMPOUNDS
ORGANIC POLYMERS
ORGANS
POLYMERIZATION
POLYMERS
RADIATIONS
VERTEBRATES
550600* - Medicine