Calculations of total activity and relative radiolysis product yields for selected photonuclear reaction target systems used for production of clinically useful, short-lived, positron-emitting radionuclides

Journal Article · Fri May 01 04:00:00 EDT 1987 · Med. Phys.; (United States)

DOI:https://doi.org/10.1118/1.596141· OSTI ID:6614297

Piltingsrud, H V; Hoops, R G

The potential performance of certain photonuclear target systems designed to produce short-lived positron emitters for nuclear medicine applications was evaluated. Included were calculations of photonuclear target activity yields, relative radiolysis product yields and relative specific activities of products as a function of photonuclear target shapes, dimensions, spacing from the bremsstrahlung photon source, and the energy of the electron beam using the reactions /sup 12/C(..gamma..,n)/sup 11/C, /sup 14/N(..gamma..,n)/sup 13/N, and /sup 16/O(..gamma..,n)/sup 15/O. Results indicate that substantial activity yields can be achieved in these photonuclear target systems and that specific activity of the product varies widely as a function of the energy of the electron beam used to produce the bremsstrahlung and the included angle from the central beam axis that the photonuclear target occupies. Results indicate that several commercial radiotherapy accelerators appear to have electron beam energy and current capabilities suitable for producing multiple mCi (1 mCi = 3.7 x 10/sup 7/ Bq) amounts of the above radionuclides.

• Research Organization: Nuclear Medicine Laboratory, Division of Physical Sciences, Office of Science and Technology, Center for Devices and Radiological Health, Food and Drug Administration, University Hospital, Cincinnati, Ohio 45267; The Eugene L. Saenger Radioisotope Laboratory, University Hospital, Cincinnati, Ohio 45267
• OSTI ID: 6614297
• Journal Information: Med. Phys.; (United States), Journal Name: Med. Phys.; (United States) Vol. 14:3; ISSN MPHYA
• Country of Publication: United States
• Language: English

Related Subjects

550604* -- Medicine-- Unsealed Radionuclides in Therapy-- (1980-)
62 RADIOLOGY AND NUCLEAR MEDICINE
BETA DECAY RADIOISOTOPES
BETA-PLUS DECAY RADIOISOTOPES
CARBON 11
CARBON 12 TARGET
CARBON ISOTOPES
ELECTRON CAPTURE RADIOISOTOPES
EVEN-ODD NUCLEI
ISOTOPES
LIGHT NUCLEI
MEDICINE
MINUTES LIVING RADIOISOTOPES
NITROGEN 13
NITROGEN 14 TARGET
NITROGEN ISOTOPES
NUCLEAR MEDICINE
NUCLEAR REACTION YIELD
NUCLEAR REACTIONS
NUCLEI
ODD-EVEN NUCLEI
OXYGEN 15
OXYGEN 16 TARGET
OXYGEN ISOTOPES
PARTICLE SOURCES
PERFORMANCE TESTING
PHOTONUCLEAR REACTIONS
POSITRON SOURCES
RADIATION SOURCES
RADIOACTIVITY
RADIOISOTOPES
RADIOLOGY
RADIOTHERAPY
TARGETS
TESTING
THERAPY
YIELDS