AIDS-related Kaposi sarcoma: findings on thallium-201 scintigraphy

Journal Article · Thu Dec 01 04:00:00 EST 1988 · AJR, Am. J. Roentgenol.; (United States)

DOI:https://doi.org/10.2214/ajr.151.6.1233· OSTI ID:6604755

Lee, V W; Rosen, M P; Baum, A; Cohen, S E; Cooley, T P; Liebman, H A

No simple, noninvasive method is available for evaluating extracutaneous Kaposi sarcoma in AIDS patients or for following the tumor's response to treatment. We report our preliminary experience with thallium-201 scintigraphy in nine AIDS patients with proved Kaposi sarcoma. Eight of the nine had abnormal uptake of the radionuclide in skin, lymph nodes, oral cavity, vagina, and lungs. Only four of the nine had cutaneous Kaposi sarcoma at the time of scanning. All cutaneous and mucosal lesions were thallium avid. Two of the six patients with thallium-avid nodes underwent nodal biopsy. Both biopsies confirmed the diagnosis of Kaposi sarcoma. Cutaneous Kaposi sarcoma developed later in one of these patients, showing the efficacy of thallium scintigraphy for the early detection of extracutaneous lesions. These preliminary results show thallium avidity in Kaposi sarcoma involving the skin and various extracutaneous sites (lymph nodes, lung, mucosa, and vagina). Thallium scintigraphy is a potentially useful procedure for detecting extracutaneous Kaposi sarcoma in AIDS patients.

• Research Organization: Boston Univ. School of Medicine, MA (USA)
• OSTI ID: 6604755
• Journal Information: AJR, Am. J. Roentgenol.; (United States), Journal Name: AJR, Am. J. Roentgenol.; (United States) Vol. 151:6; ISSN AAJRD
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
AIDS
BETA DECAY RADIOISOTOPES
COUNTING TECHNIQUES
DAYS LIVING RADIOISOTOPES
DIAGNOSIS
DIAGNOSTIC TECHNIQUES
DIAGNOSTIC USES
DISEASES
ELECTRON CAPTURE RADIOISOTOPES
HEAVY NUCLEI
HEMIC DISEASES
IMMUNE SYSTEM DISEASES
INFECTIOUS DISEASES
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LYMPH NODES
LYMPHATIC SYSTEM
NEOPLASMS
NUCLEI
ODD-EVEN NUCLEI
PATIENTS
RADIOISOTOPE SCANNING
RADIOISOTOPES
SARCOMAS
SCINTISCANNING
SECONDS LIVING RADIOISOTOPES
THALLIUM 201
THALLIUM ISOTOPES
USES
VIRAL DISEASES