Review of the Office of Drinking Water's draft final-criteria document for ortho-meta-para-dichlorobenzene
Technical Report
·
OSTI ID:6598221
The Halogenated Organics Subcommittee of the Science Advisory Board's Environmental Health Committee completed its review of the Office of Drinking Water's Draft Final Criteria Document for ortho-meta-para-dichlorobenzene. The U.S. Environmental Protection Agency has used the weight of evidence approach in recommending a classification of B2 for drinking water based on existing animal studies. The Subcommittee concluded that the reasoning offered for the conclusion is scientifically defensible, but it is not the only defensible conclusion. In assessing the issue of carcinogenicity, a key question is the weight that should be assigned to the rat data. For purposes of this and other issues, most Subcommittee members concluded that the compound should more appropriately be classified as Category C of U.S. Environmental Protection Agency guidelines.
- Research Organization:
- Environmental Protection Agency, Washington, DC (USA). Science Advisory Board
- OSTI ID:
- 6598221
- Report Number(s):
- PB-89-109003/XAB; SAB-EHC-88-016
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
29 ENERGY PLANNING, POLICY, AND ECONOMY
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
520600 -- Environment
Aquatic-- Regulations -- (-1989)
54 ENVIRONMENTAL SCIENCES
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
CARCINOGENS
CHLORINATED AROMATIC HYDROCARBONS
DOCUMENT TYPES
DRINKING WATER
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
HYDROGEN COMPOUNDS
MATERIALS
MUTAGENS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OXYGEN COMPOUNDS
PUBLIC HEALTH
REVIEWS
TOXIC MATERIALS
WATER
290300 -- Energy Planning & Policy-- Environment
Health
& Safety
520600 -- Environment
Aquatic-- Regulations -- (-1989)
54 ENVIRONMENTAL SCIENCES
560300* -- Chemicals Metabolism & Toxicology
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AROMATICS
CARCINOGENS
CHLORINATED AROMATIC HYDROCARBONS
DOCUMENT TYPES
DRINKING WATER
HALOGENATED AROMATIC HYDROCARBONS
HAZARDS
HEALTH HAZARDS
HYDROGEN COMPOUNDS
MATERIALS
MUTAGENS
ORGANIC CHLORINE COMPOUNDS
ORGANIC COMPOUNDS
ORGANIC HALOGEN COMPOUNDS
OXYGEN COMPOUNDS
PUBLIC HEALTH
REVIEWS
TOXIC MATERIALS
WATER