Radiotherapy for choroidal melanoma. An 18-year experience with radon

Journal Article · Sun Mar 01 00:00:00 EST 1987 · Arch. Ophthalmol. (Chicago); (United States)

DOI:https://doi.org/10.1001/archopht.1987.01060030072029· OSTI ID:6591725

Davidorf, F H; Pajka, J T; Makley, Jr, T A; Kartha, M K

Twenty-three patients were treated with radon therapy for choroidal melanoma at the Ohio State University Hospitals, Columbus, between 1968 and 1976. We present an 18-year experience, including follow-up of at least eight years, in all those receiving therapy. Three patients (13%) died of metastatic disease. Four patients (17.4%) died of other causes. Sixteen patients (69.6%) were alive, with no signs of metastatic disease. Eight patients subsequently required enucleation due to inadequate tumor response. Of the 15 patients who demonstrated successful tumor destruction and retained their eyes, 13 (86.7%) developed substantial irradiation-induced retinopathy, including hard exudates, telangiectasias, neovascularization, microaneurysms, intraretinal and vitreous hemorrhages, secondary glaucoma, and irradiation-induced cataract. Our long-term results indicate a high incidence of both vascular complications and decreased visual acuity.

• Research Organization: Ohio State Univ., Columbus
• OSTI ID: 6591725
• Journal Information: Arch. Ophthalmol. (Chicago); (United States), Vol. 3
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
CATARACTS
RADIOINDUCTION
EYES
MELANOMAS
RADIOTHERAPY
SIDE EFFECTS
SENSE ORGANS DISEASES
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HEAD
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RADIATION EFFECTS
RADIOLOGY
SENSE ORGANS
THERAPY
550603* - Medicine- External Radiation in Therapy- (1980-)
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