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Quantitative comparison of two radiocolloids for lymphoscintigraphy

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6589103
Recent qualitative studies suggest that a micro Tc-99m sulfur colloid (..mu..SC) offers clinically acceptable images of the lymphatic system following intradermal injection. The authors have prospectively compared ..mu..SC to Tc-99m antimony colloid (SbS), the current agent of choice, in patients (pts) undergoing internal mammary lymphoscintigraphy. Twenty-eight consecutive females from 32-76 yrs of age were studied; 14 received SbS and 14 received ..mu..SC, (1.0 mCi, subcostal in posterior rectus sheath). Images (gamma camera and computer) of the injection site, anterior thorax and a Co-57 standard at the sternal notch were obtained at time 0 and 3 hrs after injection. The difference in X-bar% lymph node uptake was not statistically significant for the two groups. The clinical information obtained with the two radiocolloids was similar with respect to number of nodes seen, migration and relative ''brightness'' (ratio-node/Co-57). Additional patient studies will be needed to confirm this observation.
Research Organization:
Dana-Farber Cancer Institute, Boston, MA
OSTI ID:
6589103
Report Number(s):
CONF-840619-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
Country of Publication:
United States
Language:
English