Assignment of the protein kinase C [delta] polypeptide gene (PRKCD) to human chromosome 3 and mouse chromosome 14
Journal Article
·
· Genomics; (United States)
- Molecular Genetics Section Lab. of Genetics, Bethesda, MD (United States)
The protein kinase C (pkc) enzymes are a family of serine-threonine protein kinases, each encoded by a distinct and separate gene. The chromosomal locations of human PRKCA, PRKCB, and PRKCG have previously been established. The authors now report that PRKCD, a novel member of the pkc gene family, maps to human chromosome 3. The chromosomal location of Pkcd has also been determined in the mouse by analysis of recombination frequency in an interspecific panel of back-cross mice. They find that the locus encoding pkcd resides proximal to nucleoside phosphorylase (Np-2) and Tcra on mouse chromosome 14 in a region syntenic with human 3p. 9 refs., 2 tabs.
- OSTI ID:
- 6588866
- Journal Information:
- Genomics; (United States), Journal Name: Genomics; (United States) Vol. 19:1; ISSN GNMCEP; ISSN 0888-7543
- Country of Publication:
- United States
- Language:
- English
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