Environment and the skin
The effects of the environment on skin are surveyed. Specific patterns of adverse skin response can be characterized by morphological, physiological, and biochemical features. Cutaneous defenses and adaptations of the skin are discussed. Dermal resiliency, epidermal and pigment components, neural components, immunobiological processes, and the epidermal barrier are examined. Percutaneous absorption is reviewed. Environmental factors that cause adverse skin reactions include water, salts of heavy metals, hydrocarbons, solvents, lipids, aromatics, esters, ultraviolet light, and various modalities of ionizing radiation. Pathologic patterns and reaction sites are discussed in terms of inflammatory, allergic, benign epidermal, eccrine sweat gland, and pilosebaceous reactions, pigmentary disturbances, cancer, and blood vessel changes. Although critical epidemiologic data are limited, cutaneous illnesses constitute a significant segment of occupational disease. Recommendations for further research are summarized. 42 references.
- Research Organization:
- Univ of Cincinnati
- OSTI ID:
- 6585836
- Journal Information:
- Environ. Health Perspect.; (United States), Vol. 20
- Country of Publication:
- United States
- Language:
- English
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SKIN
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BIOLOGICAL RADIATION EFFECTS
HYDROCARBONS
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SALTS
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