Regional uptake of (/sup 35/S)-cysteine in rat brain after arterial injection

Journal Article · Thu Jul 01 00:00:00 EDT 1982 · Res. Commun. Chem. Pathol. Pharmacol.; (United States)

OSTI ID:6585410

Misra, C H; Hicks, P; Rolsten, C; Smith, R C

The brain uptake index of (/sup 35/S)-cysteine in ten rat brain regions and in the eye was determined by measuring (/sup 35/S)-cysteine remaining in the brain regions and in the eye, five seconds after carotid injection, relative to a simultaneously injected diffusible internal standard, /sup 3/H/sub 2/O and a non-diffusible internal standard Tc99m-Sn-DTPA. A statistical comparison for the regions that receive their blood supply from the internal carotid artery was done. Only the diencephalon and the septum-nucleus accumbens were found significantly higher than cortex.

• Research Organization: Section of Biological Psychiatry, Texas Research Institute of Mental Sciences, Houston, TX
• OSTI ID: 6585410
• Journal Information: Res. Commun. Chem. Pathol. Pharmacol.; (United States), Vol. 37:1
• Country of Publication: United States
• Language: English

Related Subjects

59 BASIC BIOLOGICAL SCIENCES
BRAIN
CYSTEINE
UPTAKE
CAROTID ARTERIES
EYES
INJECTION
ISOMERIC NUCLEI
LABELLED COMPOUNDS
RATS
SULFUR 35
TECHNETIUM 99
TIN
TRITIUM COMPOUNDS
WATER
AMINO ACIDS
ANIMALS
ARTERIES
BETA DECAY RADIOISOTOPES
BETA-MINUS DECAY RADIOISOTOPES
BLOOD VESSELS
BODY
BODY AREAS
CARBOXYLIC ACIDS
CARDIOVASCULAR SYSTEM
CENTRAL NERVOUS SYSTEM
DAYS LIVING RADIOISOTOPES
ELEMENTS
EVEN-ODD NUCLEI
FACE
HEAD
HOURS LIVING RADIOISOTOPES
HYDROGEN COMPOUNDS
INTAKE
INTERMEDIATE MASS NUCLEI
ISOMERIC TRANSITION ISOTOPES
ISOTOPES
LIGHT NUCLEI
MAMMALS
METALS
NERVOUS SYSTEM
NUCLEI
ODD-EVEN NUCLEI
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC SULFUR COMPOUNDS
ORGANS
OXYGEN COMPOUNDS
RADIOISOTOPES
RODENTS
SENSE ORGANS
SULFUR ISOTOPES
TECHNETIUM ISOTOPES
THIOLS
VERTEBRATES
YEARS LIVING RADIOISOTOPES
550501* - Metabolism- Tracer Techniques