Comparative evaluation of NMR and nuclear medicine in disc space infection: A pilot study
Six patients with proven disc space infection underwent bone scanning with 975MB/sub q/ HDP together with NMR imaging on a 0.6T superconducting magnet to obtain weighted T1 30mSec (TE .3 Sec TR) and T2 (120mSec TE 3 Sec TR) images within a 48 hr. period. All patients had plain radiographic evaluation of the areas involved. Three pts. had Ga-67 Citrate scans using 222MBq activity following the bone scan and 1 patient had CT images of the involved area. All 6 bone scans showed increased bony uptake in at least the adjacent vertebral end plates but did not show any abnormal uptake in the region of the disc. Bony activity distribution was non-specific and could have been consistent with either degenerative or osteomyelitic change. Gallium imaging in one case supported the latter diagnosis but did not indicate presence of disc space involvement. Two other cases showed bony involvement to the extent of the bone scan; one showing minimal uptake due to antibiotic therapy. Plain radiographs were suggestive of disc space infection in all cases. NMR in all cases revealed marked disc space and adjacent bone involvement to the extent shown on bone scans. T1 and T2 weighted images appeared highly specific for either infection or degenerative change and were unaffected by antibiotic therapy. NMR appears to be more sensitive in evaluation of disc space infection than radionuclide studies. NMR is also able to provide significant anatomic information involving thecal sac and neural structures. Nuclear medicine studies appear equally sensitive though less specific in the evaluation of bone involvement except perhaps where antibiotic therapy has been used.
- Research Organization:
- Cleveland Clinic Foundation, Cleveland, OH
- OSTI ID:
- 6574219
- Report Number(s):
- CONF-840619-; TRN: 87-018986
- Journal Information:
- J. Nucl. Med.; (United States), Vol. 25:5; Conference: 31. annual meeting of the Society of Nuclear Medicine, Los Angeles, CA, USA, 5 Jun 1984
- Country of Publication:
- United States
- Language:
- English
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59 BASIC BIOLOGICAL SCIENCES
CAT SCANNING
COMPARATIVE EVALUATIONS
NMR IMAGING
SCINTISCANNING
ANATOMY
ANTIBIOTICS
BONE TISSUES
IMAGES
IMMUNOTHERAPY
RADIOPHARMACEUTICALS
SENSITIVITY
THERAPY
TISSUE DISTRIBUTION
UPTAKE
ANIMAL TISSUES
ANTI-INFECTIVE AGENTS
BODY
COMPUTERIZED TOMOGRAPHY
CONNECTIVE TISSUE
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISTRIBUTION
DRUGS
LABELLED COMPOUNDS
RADIOISOTOPE SCANNING
TISSUES
TOMOGRAPHY
550602* - Medicine- External Radiation in Diagnostics- (1980-)
550800 - Morphology