Cardiac lymphoscintigraphy following closed-chest catheter injection of radiolabeled colloid into the myocardium of dogs: concise communication

Journal Article · Fri Oct 01 04:00:00 EDT 1982 · J. Nucl. Med.; (United States)

OSTI ID:6569389

Osbakken, M D; Kopiwoda, S Y; Swan, A; Castronovo, F P; Strauss, H W

A catheter technique for injection of radiolabeled colloids into the myocardium was developed and tested in a series of 15 dogs. A multipurpose angiographic catheter was modified to permit an inner core of PE-50 polyethylene tubing, tipped with a 23-gage needle, to pass through the lumen for intra-myocardial injection of radiocolloids. For injection of the left ventricle, the catheter is introduced through the femoral artery: for the right ventricle, the femoral vein. The catheter advanced under fluoroscopy until the desired surface for injection is reached. The inner core is then extended to lodge the needle in the endocardium. A mixture of Renografin (to confirm the endocardial injection site) and radiolabeled colloid was injected in 13 animals. Ten minutes after injection, scintigraphy was begun and continued for up to 6 hr. In three dogs the procedure was repeated 3 or 4 times. From two to five nodes were visible in all animals, irrespective of whether the right or left ventricular myocardium was injected. In two animals the injection was given intravenously, and no nodes were seen. These data suggest that cardiac lymphatic drainage can be studied with a catheter injection method.

• Research Organization: Massachusetts General Hospital, Boston
• OSTI ID: 6569389
• Journal Information: J. Nucl. Med.; (United States), Journal Name: J. Nucl. Med.; (United States) Vol. 23:10; ISSN JNMEA
• Country of Publication: United States
• Language: English

Related Subjects

550601* -- Medicine-- Unsealed Radionuclides in Diagnostics
62 RADIOLOGY AND NUCLEAR MEDICINE
ANIMALS
BIOMEDICAL RADIOGRAPHY
BODY
CARDIOVASCULAR SYSTEM
COLLOIDS
COUNTING TECHNIQUES
DIAGNOSTIC TECHNIQUES
DISPERSIONS
DOGS
FLUOROSCOPY
HEART
INJECTION
INTAKE
LYMPH NODES
LYMPHATIC SYSTEM
MAMMALS
MEDICINE
MUSCLES
MYOCARDIUM
NUCLEAR MEDICINE
ORGANS
RADIOCOLLOIDS
RADIOISOTOPE SCANNING
RADIOLOGY
SCINTISCANNING
VERTEBRATES