Improved detection of Mycobacterium avium complex with the Bactec radiometric system
A reconsideration of the laboratory methods used for primary isolation of mycobacteria other than Mycobacterium tuberculosis is needed due to the increasingly recognized importance of such mycobacterial infections in immunocompromised patients. One example of this is the severe opportunistic infections caused by Mycobacterium avium complex among AIDS patients. In this study, the Bactec radiometric system was compared to conventional culture on solid medium for the detection of M. avium complex in 3,612 selected clinical specimens, mainly of extrapulmonary origin. Of a total number of 63 M. avium complex isolates, the Bactec system detected 58 (92%), compared to 37 (59%) for conventional culture. A much more rapid detection was attained with radiometric technique than with conventional culture. The mean detection time for the cultures positive with both methods was 7.1 and 28.3 days, respectively. The Bactec radiometric system achieves a rapid and significantly more sensitive detection and seems to be an excellent complement to conventional culture in the laboratory diagnosis of infections with the M. avium complex.
- Research Organization:
- National Bacteriological Laboratory, Stockholm (Sweden)
- OSTI ID:
- 6556172
- Journal Information:
- Diagn. Microbiol. Infect. Dis.; (United States), Vol. 10:1
- Country of Publication:
- United States
- Language:
- English
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Related Subjects
62 RADIOLOGY AND NUCLEAR MEDICINE
BACTERIAL DISEASES
DIAGNOSIS
MYCOBACTERIUM TUBERCULOSIS
RADIOMETRIC ANALYSIS
AIDS
CARBON DIOXIDE
PATIENTS
SENSITIVITY ANALYSIS
BACTERIA
CARBON COMPOUNDS
CARBON OXIDES
CHALCOGENIDES
CHEMICAL ANALYSIS
DISEASES
HEMIC DISEASES
IMMUNE SYSTEM DISEASES
INFECTIOUS DISEASES
MICROORGANISMS
MYCOBACTERIUM
OXIDES
OXYGEN COMPOUNDS
QUANTITATIVE CHEMICAL ANALYSIS
VIRAL DISEASES
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