Separation of alkylphenols by normal-phase and reversed-phase high-performance liquid chromatography

Journal Article · Wed Nov 01 00:00:00 EST 1978 · Anal. Chem.; (United States)

DOI:https://doi.org/10.1021/ac50035a046· OSTI ID:6555980

Schabron, J F; Hurtubise, R J; Silver, H F

Empirical correlation factors were developed which relate log k' values for alkylphenols, the naphthols, and two phenylphenols to structural features. Both normal-phase and reversed-phase chromatographic systems were studied. The stationary phases employed in the normal-phase work were ..mu..-Bondapak CN, ..mu..-Bondapak NH/sub 2/, and ..mu..-Porasil. The structural features which affect retention in the normal-phase chromatographic systems are the number of ortho substituents, the number of aliphatic carbons, and the number of aromatic rings. The stationary phases employed in the reversed-phase work were ..mu..-Bondapak C/sub 18/ and ..mu..-Bondapak CN. The structural features which affect retention in the reversed-phase chromatographic systems are the number of aliphatic carbons and the number of aromatic double bonds. On ..mu..-Bondapak C/sub 18/, the presence or absence of a nonaromatic ring is of added importance.

• Research Organization: Univ. of Wyoming, Laramie
• OSTI ID: 6555980
• Journal Information: Anal. Chem.; (United States), Vol. 50:13
• Country of Publication: United States
• Language: English

Related Subjects

37 INORGANIC
ORGANIC
PHYSICAL AND ANALYTICAL CHEMISTRY
PHENOLS
LIQUID COLUMN CHROMATOGRAPHY
COAL LIQUIDS
CORRELATIONS
ION EXCHANGE MATERIALS
MIXTURES
RETENTION
SEPARATION PROCESSES
STANDARDS
AROMATICS
CHROMATOGRAPHY
DISPERSIONS
HYDROXY COMPOUNDS
ORGANIC COMPOUNDS
400105* - Separation Procedures