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Nuclear magnetic resonance (NMR) blood flow imaging

Conference · · J. Nucl. Med.; (United States)
OSTI ID:6546895
Picture element values in NMR images are dependent not only upon T/sub 1/ and T/sub 2/ relaxation times but also on the local density and velocity of hydrogen nuclei moving through the region being imaged. In 1959 the potential of non-imaging NMR for measuring blood flow was demonstrated. Recently several investigators have proposed methods for combining NMR imaging with NMR blood flow measurements. The authors have investigated the relationships between various radiofrequency pulse sequences and flow rate and their effects on image intensity using a constant flow pump and a 0.5 Tesla Technicare Teslacon NMR imager. Dilute mixtures of ethylene glycol were used to simulate blood. Flow measurements were made in Tygon Tubing (12 mm) at variable velocities ranging from 0-35 cm/sec. The flow phantom was used to calibrate several pulse sequences relating image intensity and vascular flow velocity. Representative patient studies demonstrating blood-flow have been performed. The calibration is being extended to pulsatile flow systems.
Research Organization:
Vanderbilt Univ. School of Medicine, Nashville, TN
OSTI ID:
6546895
Report Number(s):
CONF-840619-
Conference Information:
Journal Name: J. Nucl. Med.; (United States) Journal Volume: 25:5
Country of Publication:
United States
Language:
English