Atmospheric reactions of polycyclic aromatic hydrocarbons: facile formation of mutagenic nitro derivatives

Journal Article · Fri Nov 03 04:00:00 UTC 1978 · Science; (United States)

DOI:https://doi.org/10.1126/science.705341· OSTI ID:6540294

Pitts, Jr, J N; Van Cauwenberghe, K A; Grosjean, D; Schmid, J P; Fitz, D R; Belser, W L; Knudson, G P; Hynds, P M

Directly active mutagens are formed on exposure of the promutagen benzo(a)pyrene to gaseous pollutants in smog. In simulated atmospheres containing 1 part per million nitrogen dioxide and traces of nitric acid, directly mutagenic nitro derivatives are readily formed from both benzo(a)pyrene and perylene, a non-mutagen in the Ames reversion assay. Possible formation of direct mutagens by such reactions on sample collection filters, in exhaust effluents, and in the atmosphere should be recognized.

• OSTI ID: 6540294
• Journal Information: Science; (United States), Journal Name: Science; (United States) Vol. 202:4367; ISSN SCIEA
• Country of Publication: United States
• Language: English

Related Subjects

500200* -- Environment
Atmospheric-- Chemicals Monitoring & Transport-- (-1989)
54 ENVIRONMENTAL SCIENCES
AIR POLLUTION
AROMATICS
BENZOPYRENE
CHEMICAL EFFLUENTS
CHEMICAL REACTIONS
CHEMISTRY
CONDENSED AROMATICS
EARTH ATMOSPHERE
HYDROCARBONS
MUTAGEN SCREENING
MUTAGENS
ORGANIC COMPOUNDS
PHOTOCHEMISTRY
POLLUTION
POLYCYCLIC AROMATIC HYDROCARBONS
REACTION INTERMEDIATES
REDOX REACTIONS
SAMPLING
SCREENING
SMOG