Placental transfer of lead, mercury, cadmium, and carbon monoxide in women. II. Influence of some epidemiological factors on the frequency distributions of the biological indices in maternal and umbilical cord blood
We have investigated the influence of various epidemiological factors (smoking habits, residence, age, occupation, drinking habits, duration of pregnancy, number of previous pregnancies) in the exposure of 474 European pregnant women and their newborns to lead, mercury, cadmium, and carbon monoxide. Smoking has a statistically significant influence on carboxyhemoglobin level in mothers and newborns and on cadmium concentration in maternal blood. The association of smoking with a reduction of fetal weight was confirmed. A slight but statistically significant effect of environmental pollution by lead (urban and industrial > semirural > rural area) on lead uptake by the pregnant mothers and its transfer to their fetuses was demonstrated. Some results suggest that during pregnancy lead could be mobilized from maternal tissue depots, but further investigations are required to confirm this tentative conclusion. No significant relationships were found between the other epidemiological parameters and the various biological measurements performed on mother and cord blood.
- Research Organization:
- Univ. of Louvain, Brussels
- OSTI ID:
- 6539381
- Journal Information:
- Environ. Res.; (United States), Journal Name: Environ. Res.; (United States) Vol. 15:3; ISSN ENVRA
- Country of Publication:
- United States
- Language:
- English
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Placental transfer of lead, mercury, cadmium, and carbon monoxide in women. III. Factors influencing the accumulation of heavy metals in the placenta and the relationship between metal concentration in the placenta and in maternal and cord blood
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Related Subjects
560306* -- Chemicals Metabolism & Toxicology-- Man-- (-1987)
59 BASIC BIOLOGICAL SCIENCES
63 RADIATION, THERMAL, AND OTHER ENVIRON. POLLUTANT EFFECTS ON LIVING ORGS. AND BIOL. MAT.
AEROSOLS
AGE DEPENDENCE
ANIMALS
BIOLOGICAL ACCUMULATION
BIOLOGICAL MATERIALS
BLOOD
BODY FLUIDS
CADMIUM
CARBON COMPOUNDS
CARBON MONOXIDE
CARBON OXIDES
CARBOXYHEMOGLOBIN
CHALCOGENIDES
COLLOIDS
DISPERSIONS
ELEMENTS
FEMALES
FETAL MEMBRANES
FETUSES
LEAD
MAMMALS
MAN
MEMBRANES
MERCURY
METALS
OCCUPATIONS
OXIDES
OXYGEN COMPOUNDS
PLACENTA
POLLUTION
PREGNANCY
PRIMATES
RESIDUES
SMOKES
SOLS
TOBACCO SMOKES
UPTAKE
VERTEBRATES
WOMEN