The effect of propionic acid and valeric acid on the cell cycle in root meristems of Pisum sativum

Journal Article · Mon Jan 01 04:00:00 EST 1990 · American Journal of Botany; (USA)

OSTI ID:6531701

Tramontano, W A; Yang, Shauyu; Delillo, A R ^[1]

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1. Manhattan College, Riverdale, NY (USA)

Propionic acid and valeric acid at 1mM reduced the mitotic index of root meristem cells of Pisum sativum to < 1% after 12 hr in aerated White's medium. This effect varied with different acid concentrations. After a 12 hr exposure to either acid, seedlings transferred to fresh medium without either acid, resumed their normal mitotic index after 12 hr, with a burst of mitosis 8 hr post-transfer. Exposure of root meristem cells to either acid also inhibited ({sup 3}H)-TdR incorporation. Neither acid significantly altered the distribution of meristematic cells in G1 and G2 after 12 hr. The incorporation of ({sup 3}H) - uridine was also unaltered by the addition of either acid. This information suggests that propionic acid and valeric acid, limit progression through the cell cycle by inhibiting DNA synthesis and arresting cells in G1 and G2. These results were consistent with previous data which utilized butyric acid.

• OSTI ID: 6531701
• Journal Information: American Journal of Botany; (USA), Journal Name: American Journal of Botany; (USA); ISSN 0002-9122; ISSN AJBOA
• Country of Publication: United States
• Language: English

Related Subjects

550201* -- Biochemistry-- Tracer Techniques
59 BASIC BIOLOGICAL SCIENCES
AZINES
BIOLOGICAL EFFECTS
CARBOXYLIC ACIDS
CELL CYCLE
CELL DIVISION
HETEROCYCLIC COMPOUNDS
HYDROGEN COMPOUNDS
HYDROXY COMPOUNDS
ISOTOPE APPLICATIONS
LEGUMINOSAE
MAGNOLIOPHYTA
MAGNOLIOPSIDA
MITOSIS
MITOTIC INDEX
MONOCARBOXYLIC ACIDS
NUCLEOSIDES
NUCLEOTIDES
ORGANIC ACIDS
ORGANIC COMPOUNDS
ORGANIC NITROGEN COMPOUNDS
PISUM
PLANTS
PROPIONIC ACID
PYRIMIDINES
RIBOSIDES
SEEDLINGS
TRACER TECHNIQUES
TRITIUM COMPOUNDS
URACILS
URIDINE
VALERIC ACID